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SHL Medical and MoonLake Immunotherapeutics collaborate to develop sonelokimab autoinjector


News provided by

SHL Medical

03 May, 2023, 12:58 GMT

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ZUG, Switerland, May 3, 2023 /PRNewswire/ -- SHL Medical, a world-leading provider of advanced drug delivery solutions, announced that it has signed a collaboration agreement with MoonLake Immunotherapeutics, a clinical-stage biotechnology company focused on creating next-level therapies for inflammatory diseases, to develop an autoinjector for clinical and potential commercial supply of MoonLake's Nanobody® sonelokimab based on SHL Medical's Molly® autoinjector technology.

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SHL Medical to develop Molly® autoinjector for MoonLake Immunotherapeutics’ sonelokimab

Sonelokimab is MoonLake Immunotherapeutics' investigational anti-IL-17 A/F Nanobody technology designed to more directly target sites of inflammation and penetrate difficult-to-reach inflamed tissues and joints. A ~40 kDa molecule, sonelokimab can be delivered subcutaneously by patients via self-injection devices, including in a patient-centric autoinjector format. Sonelokimab is currently in clinical development for several indications, including moderate-to-severe plaque-type psoriasis and hidradenitis suppurativa, a severely debilitating chronic skin condition resulting in irreversible tissue destruction.

The Molly autoinjector is a market-proven modular platform technology developed to help pharmaceutical and biotechnology companies reduce initial investments and expedite development timelines. The maturity of the Molly platform has made it a trusted drug delivery device solution, particularly for innovative biotechnology companies seeking to lower the risks for their autoinjector projects. Refined over the years through SHL Medical's team of experts and industry-leading efforts, the Molly technology is also indicative of how modularity built upon an established platform can enable efficient, scalable production geared towards the end goal of enabling patients' independence. To date, a total of 17 combination products that leverage the Molly autoinjector technology have been approved in at least 69 countries, enabling home treatment in a wide range of therapeutic areas that require injectable medicines, including for dermatologic and inflammatory indications.

Under the scope of the agreement, SHL Medical will provide its device development expertise, assembly guidance, and production competencies to support the sonelokimab drug-device project. The collaboration highlights SHL Medical's capabilities as a fully integrated, end-to-end solutions provider offering added value for its pharmaceutical and biotechnology partner's autoinjector projects, from robust device solutions to production and after-market needs.

"SHL Medical and MoonLake are united by our shared passion for pursuing innovation and going beyond to deliver novel therapies that help unlock value and improve patients' lives," said SHL Medical Chief Executive Officer Ulrich Faessler. "Working with MoonLake while sonelokimab is in development allows us to carry out strategies that best complement MoonLake's clinical and commercial needs. We are excited about the collaboration and look forward to potentially bringing the innovative Nanobody technology for dermatologic and rheumatic inflammatory indications to patients worldwide."

Oliver Daltrop, Chief Technical Officer of MoonLake Immunotherapeutics, added: "MoonLake is proud to be partnering with a world leader in advanced autoinjector development to provide sonelokimab for clinical and potentially commercial supply. As we actively plan for a Phase 3 program and commercial readiness, SHL's expertise will greatly enhance our ability to introduce sonelokimab in an autoinjector format that could provide a benefit for patients, if approved."

Note: Nanobody® and Nanobodies® are (registered) trademarks of Ablynx, a Sanofi company.

About SHL Medical

SHL Medical is a world-leading solutions provider in the design, development, and manufacturing of advanced delivery devices such as autoinjectors, pen injectors, and innovative specialty delivery systems for large-volume and high-viscosity formulations. It offers final assembly, labeling, and packaging solutions for its drug delivery devices, and also provides contract manufacturing and engineering services for the production of complex medtech and industrial products.

With locations in Switzerland, Taiwan, Sweden, and the US, SHL Medical's experienced designers and engineers develop product enhancements and breakthrough drug delivery solutions for pharma and biotech clients globally. Significant investments in R&D have enhanced its broad pipeline of next-generation drug delivery systems that support ongoing innovations in drug development and digital healthcare. This includes advanced reusable and disposable injectors that can accommodate large-volume and high-viscosity formulations and can be enhanced through digital implementations.

For additional information, visit https://www.shl-medical.com/.

About MoonLake Immunotherapeutics

MoonLake Immunotherapeutics is a clinical-stage biopharmaceutical company unlocking the potential of sonelokimab, a novel investigational Nanobody® technology for the treatment of inflammatory disease, to revolutionize outcomes for patients. Sonelokimab inhibits IL-17A and IL-17F by inhibiting the IL-17A/A, IL-17A/F, and IL-17F/F dimers that drive inflammation. The company's focus is on inflammatory diseases with a major unmet need, including hidradenitis suppurativa and psoriatic arthritis – conditions affecting millions of people worldwide with a large need for improved treatment options. MoonLake was founded in 2021 and is headquartered in Zug, Switzerland. Further information is available at www.moonlaketx.com.

Media contact

Carl Gillblad
Corporate Communications
info@shl-medical.com
+41 41 368 00 00

Photo - https://mma.prnewswire.com/media/2068688/Press_Release_SHL_MoonLake_PRNewswire_Molly_autoinjector_inflamatory_skin_injection_therapy_1800x853.jpg 

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