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Herpes Simplex 7MM Market Size is Projected to Grow at a CAGR of 4.4% by 2034 | DelveInsight

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DelveInsight Business Research, LLP

11 Feb, 2025, 22:31 GMT

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The overall market of herpes simplex is expected to boost with the expected launch of emerging therapy, increased awareness, and extensive research in the forecast period (2025–2034).

LAS VEGAS, Feb. 11, 2025 /PRNewswire/ -- DelveInsight's Herpes Simplex Market Insights report includes a comprehensive understanding of current treatment practices, herpes simplex emerging drugs, market share of individual therapies, and current and forecasted market size from 2020 to 2034, segmented into 7MM [the United States, the EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan].

Key Takeaways from the Herpes Simplex Market Report

  • According to DelveInsight's analysis, the market size for herpes simplex was found to be USD 3.1 billion in the 7MM in 2023.
  • There were 13 million total diagnosed cases of HSV estimated to have occurred in the 7MM in 2023 of which 4.9 million of the accounted cases were estimated to be from the US alone and these cases are anticipated to decrease in the foreseeable future during the study period.
  • Leading herpes simplex companies such as AiCuris Anti-infective Cures AG, ModernaTX, BioNTech SE, and others are developing novel herpes simplex drugs that can be available in the herpes simplex market in the coming years.
  • The promising herpes simplex therapies in the pipeline include PRITELIVIR (AIC-316), mRNA-1608, BNT163, and others.
  • The emerging drug PRITELIVIR is expected to launch in the US market by 2026, in the UK by 2027, and in Japan by 2027, which has the potential to reduce the disease burden of Herpes Simplex in the forecasted years.

Discover which therapies are expected to grab the major herpes simplex market share @ Herpes Simplex Market Report

Herpes Simplex Overview

The herpes simplex virus (HSV) is divided into two types: HSV-1 and HSV-2. HSV-1 typically leads to oral herpes, manifesting as cold sores or fever blisters around the mouth and face, while HSV-2 is usually responsible for genital herpes, causing painful sores, itching, and discomfort in the genital region. HSV is transmitted through direct contact with infected bodily fluids, most commonly during oral, genital, or anal sexual activities. It can also spread through oral-to-oral contact, such as kissing, and from mother to infant during vaginal childbirth, known as vertical transmission.

Diagnosing HSV infections involves clinical evaluation, examination of lesions, and laboratory tests. Common diagnostic methods include polymerase chain reaction (PCR) tests, viral culture, and serologic tests for HSV-specific antibodies. PCR is particularly effective for detecting viral DNA in lesions, while serologic tests help identify previous exposure to HSV-1 or HSV-2.

Herpes Simplex Epidemiology Segmentation

The herpes simplex epidemiology section provides insights into the historical and current herpes simplex patient pool and forecasted trends for the 7MM. It helps recognize the causes of current and forecasted patient trends by exploring numerous studies and views of key opinion leaders.

The herpes simplex market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into:

  • Total Seroprevalence of HSV
  • Total Symptomatic Cases of HSV
  • Total Diagnosed Cases of HSV
  • Gender-specific Diagnosed Cases of HSV
  • Total Recurrent Cases of HSV 

Herpes Simplex Treatment Market 

The treatment of herpes simplex primarily involves oral antiviral medications, which can occasionally cause gastrointestinal issues or headaches. These therapies are highly regarded for their safety and their ability to activate only in virus-infected cells, enhancing both tolerability and effectiveness. In severe cases, antiviral treatments such as acyclovir, valacyclovir, and famciclovir are used to address the complex hormonal influences and inhibit viral DNA synthesis by targeting viral DNA polymerase. 

Oral therapies are also beneficial in managing recurrent infections. When HSV-1 reactivates from its dormant state in the trigeminal ganglion, it leads to symptomatic outbreaks, commonly known as cold sores, around the mouth. Recurrent mucosal HSV-1 infections usually have milder symptoms and resolve more quickly than initial infections. Supportive care, including patient education, assessment, monitoring, and counseling, is crucial for ensuring effective management and adherence to treatment, thereby optimizing outcomes.

Although no cure exists, antiviral medications such as acyclovir, famciclovir, and valacyclovir are frequently prescribed to speed up healing during initial or recurrent herpes outbreaks. These drugs can lessen the severity and duration of symptoms but do not eliminate the infection. It's essential to begin treatment within 48 hours of symptom onset to effectively manage recurrent outbreaks, especially for those with frequent or painful episodes or those aiming to reduce transmission risk.

Given that current strategies are inadequate for fully managing the disease burden, there is an urgent need for the development of new therapies.

To know more about herpes simplex treatment guidelines, visit @ Herpes Simplex Management 

Herpes Simplex Pipeline Therapies and Key Companies

  • PRITELIVIR (AIC-316): AiCuris Anti-infective Cures AG
  • mRNA-1608: ModernaTX
  • BNT163: BioNTech SE

Discover more about herpes simplex drugs in development @ Herpes Simplex Clinical Trials 

Herpes Simplex Market Dynamics

The herpes simplex market dynamics are expected to change in the coming years. The rise in healthcare spending in developing nations has improved access to medical services, including treatment for HSV, leading to increased demand for herpes simplex virus treatments. The persistent and recurring nature of HSV infections drives a continuous need for long-term care and treatment options in the market. Partnerships between research institutions and the healthcare sector could significantly enhance the market's potential by developing more effective therapies compared to current palliative care. Additionally, raising public awareness about herpes simplex infections can lead to earlier diagnosis and treatment, ultimately benefiting the financial outlook of the market.

Furthermore, potential therapies are being investigated for the treatment of herpes simplex, and it is safe to predict that the treatment space will significantly impact the herpes simplex market during the forecast period. Moreover, the anticipated introduction of emerging therapies with improved efficacy and a further improvement in the diagnosis rate are expected to drive the growth of the herpes simplex market in the 7MM.

However several factors may impede the growth of the herpes simplex market. Herpes infections carry a significant social stigma, which discourages patients from openly seeking treatment. The condition's complex causes and symptoms that overlap with other diseases often result in misdiagnosis, further harming the market. Strict regulatory approvals deter companies from starting clinical trials, and the challenging nature of managing HSV reduces patient adherence and creates uncertainty about continuing long-term treatment, ultimately weakening the market over time.

Moreover, herpes simplex treatment poses a significant economic burden and disrupts patients' overall well-being and QOL. Furthermore, herpes simplex market growth may be offset by failures and discontinuation of emerging therapies, unaffordable pricing, market access and reimbursement issues, and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact herpes simplex market growth.

Herpes Simplex Market Report Metrics

Details

Study Period

2020–2034

Coverage

7MM [the United States, the EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan].

Herpes Simplex Market CAGR

4.4 %

Herpes Simplex Market Size in 2023

USD 3.1 Billion

Key Herpes Simplex Companies

AiCuris Anti-infective Cures AG, ModernaTX, BioNTech SE, Bioalliance Pharma, Vectans Pharma, Maruho, and others

Key Pipeline Herpes Simplex Therapies

PRITELIVIR (AIC-316), mRNA-1608, BNT163, SITAVIG (acyclovir), AMENALIEF (amenamevir), and others

Scope of the Herpes Simplex Market Report

  • Therapeutic Assessment: Herpes Simplex current marketed and emerging therapies
  • Herpes Simplex Market Dynamics: Key Market Forecast Assumptions of Emerging Herpes Simplex Drugs and Market Outlook
  • Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
  • Unmet Needs, KOL's views, Analyst's views, Herpes Simplex Market Access and Reimbursement

Download the report to understand which factors are driving herpes simplex market trends @ Herpes Simplex Market Trends

Table of Contents

1

Key Insights

2

Report Introduction

3

Herpes Simplex Market Overview at a Glance

3.1

Market Share (%) Distribution of Herpes Simplex in 2020 by Therapies

3.2

Market Share (%) Distribution of Herpes Simplex in 2034 by Therapies

4

Epidemiology and Market Forecast Methodology

5

Executive Summary

6

Key Events

7

Disease Background and Overview

7.1

Introduction

7.2

Types of Herpes Simplex

7.3

Causes and Risk Factors

7.4

Pathophysiology

7.5

Symptoms and Clinical Presentations

7.6

Diagnosis

7.6.1

Diagnostic Algorithm

7.6.2

Diagnostic Guidelines

7.6.3

Differential Diagnosis

7.7

Treatment and Management

7.7.1

Treatment Algorithm

7.7.2

Treatment Guidelines

7.7.2.1

WHO Guidelines for the treatment of genital herpes simplex virus

7.7.2.2

UK national guideline for the management of anogenital herpes

7.7.2.3

Centers for Disease Control and Prevention (CDC) Sexually Transmitted Infections Treatment Guidelines,2021

8

Epidemiology and Patient Population

8.1

Key Findings

8.2

Assumptions and Rationale: The 7MM

8.2.1

Seroprevalent Cases of HSV

8.2.2

Symptomatic Cases of HSV

8.2.3

Diagnosed Cases of HSV

8.2.4

Gender-specific Diagnosed Cases of HSV

8.2.5

Recurrent Cases of HSV

8.3

Diagnosed Cases of HSV

8.4

The United States

8.4.1

Seroprevalent Cases of HSV in the US

8.4.2

Symptomatic Cases of HSV in the US

8.4.3

Diagnosed Cases of HSV in the US

8.4.4

Gender-specific Diagnosed Cases of HSV in the US

8.4.5

Recurrent Cases of HSV in the US

8.5

EU4 and the UK

8.5.1

Seroprevalent Cases of HSV in EU4 and the UK

8.5.2

Symptomatic Cases of HSV in EU4 and the UK

8.5.3

Diagnosed Cases of HSV in EU4 and the UK

8.5.4

Gender-specific Diagnosed Cases of HSV in EU4 and the UK

8.5.5

Recurrent Cases of HSV in EU4 and the UK

8.6

Japan

8.6.1

Seroprevalent Cases of HSV in Japan

8.6.2

Symptomatic Cases of HSV in Japan

8.6.3

Diagnosed Cases of HSV in Japan

8.6.4

Gender-specific Diagnosed Cases of HSV in Japan

8.6.5

Recurrent Cases of HSV in Japan

9

Patient Journey

10

Marketed Therapies

10.1

Key Cross Competition of Marketed Drugs

10.2

SITAVIG (acyclovir): Bioalliance Pharma/Vectans Pharma

10.2.1

Product Description

10.2.2

Regulatory Milestone

10.2.3

Other Developmental Activities

10.2.4

Clinical Trials Information

10.2.5

Safety and Efficacy

10.3

AMENALIEF (amenamevir): Maruho

10.3.1

Product Description

10.3.2

Regulatory Milestone

10.3.3

Other Developmental Activities

10.3.4

Clinical Trials Information

10.3.5

Safety and Efficacy

11

Emerging Therapies

11.1

Key Cross Competition

11.2

PRITELIVIR (AIC-316): AiCuris Anti-infective Cures AG

11.2.1

Product Description

11.2.2

Other Developmental Activities

11.2.3

Clinical Trials Information

11.2.4

Safety and Efficacy

11.2.5

Analyst Views

11.4

mRNA-1608: ModernaTX

11.4.1

Product Description

11.4.2

Clinical Trials Information

11.4.3

Analyst Views

List to be continued in the report……

12

Herpes Simplex: Market Analysis

12.1

Key Findings

12.2

Key Market Forecast Assumptions

12.3

Market Outlook

12.4

Total Market Size of Herpes Simplex in the 7MM

12.5

Market Size of Herpes Simplex by Therapies in the 7MM

12.6

Market Size of Herpes Simplex in the United States

12.6.1

Total Market Size of Herpes Simplex

12.6.2

Market Size of Herpes Simplex by Therapies in the United States

12.7

Market Size of Herpes Simplex in EU4 and the UK

12.7.1

Total Market Size of Herpes Simplex

12.7.2

Market Size of Herpes Simplex by Therapies in the EU4 and the UK

12.8

Market Size of Herpes Simplex in Japan

12.8.1

Total Market Size of Herpes Simplex

12.8.2

Market Size of Herpes Simplex by Therapies in Japan

13

Key Opinion Leaders' Views

14

SWOT Analysis

15

Unmet Needs

16

Market Access and Reimbursement

16.1

The United States

16.1.1

Center for Medicare and Medicaid Services (CMS)

16.2

In EU4 and the UK

16.2.1

Germany

16.2.2

France

16.2.3

Italy

16.2.4

Spain

16.2.5

The United Kingdom

16.3

Japan

16.3.1

MHLW

17

Appendix

17.1

Bibliography

17.2

Acronyms and Abbreviations

17.3

Report Methodology

18

DelveInsight Capabilities

19

Disclaimer

Related Reports

Herpes Simplex Epidemiology Forecast

Herpes Simplex Epidemiology Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the herpes simplex epidemiology trends.

Herpes Simplex Pipeline

Herpes Simplex Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key herpes simplex companies, including RedBioTec, TGV-Laboratories, Maruho, AiCuris, Sanofi, Starpharma, ReceptoPharm, among others.

Genital Herpes Market

Genital Herpes Market Insights, Epidemiology, and Market Forecast – 2034 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key genital herpes companies, including AiCuris, United BioPharma, Heidelberg ImmunoTherapeutics, Genocea Biosciences, Agenus, Fresh Tracks Therapeutics, Sanofi, among others.

Genital Herpes Pipeline

Genital Herpes Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, including clinical and non-clinical stage products, and the key genital herpes companies, including AiCuris, United BioPharma, Assembly Biosciences, BioNTech, Innovative Molecules, among others.

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

Contact Us
Shruti Thakur
info@delveinsight.com
+14699457679
www.delveinsight.com

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