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      Presentation of ONCOS-102 Melanoma Data at SITC Annual Meeting


      News provided by

      Targovax

      11 Nov, 2019, 06:28 GMT

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      OSLO, Norway, Nov. 11, 2019 /PRNewswire/ -- Targovax ASA (OSE: TRVX), announces that clinical data from its combination trial with ONCOS-102 and Keytruda in anti-PD1 refractory melanoma was presented at the Society for Immunotherapy of Cancer (SITC) Annual Meeting

      Dr. Shoushtari, MD, Medical Oncologist, Memorial Sloan Kettering, presented results from part 1 of Targovax's phase I trial in anti-PD1 refractory melanoma combining ONCOS-102 with Keytruda. Headline data were released in July, showing that three out of nine patients had significant reduction of tumor burden (33% overall response rate, ORR), including one patient with a complete response, which is rarely seen in this late-stage patient population Please see the full presentation here: SITC presentation 

      Øystein Soug, CEO of Targovax, commented: "Although the number of patients is small, 33% ORR is very encouraging and confirms our hypothesis that ONCOS-102 can immune activate PD-1 refractory tumors to respond to re-challenge with Keytruda. We are very excited that these data are being recognized with an oral presentation at the SITC Annual Meeting."

      Part 2 of the trial is currently enrolling patients, where an extended ONCOS-102 dosing regimen is being assessed.

      An extended presentation will be given by Dr. Shoushtari at an investor event in NYC later this week:

      SOLEBURY TROUT KOL DAY

      Date:

      15 November 2019

      Time and place

      2 pm ET; NYC, US

      Presenter:

      Dr. Alexander Shoushtari, Principal Investigator, Memorial Sloan Kettering Cancer Center, NYC

      Webcast:

      https://services.choruscall.com/links/trvx191115.html

      For more information about the Solebury Trout KOL day or to RSVP, institutional investors and sell-side analysts may contact access@troutgroup.com. 

      KOL biography:

      Alexander N. Shoushtari, MD, Medical Oncologist, Memorial Sloan Kettering

      Dr. Shoushtari is a renowned expert in melanoma, with a research focus on uveal and mucosal melanomas. He has been part of several immunotherapy trials at MSKCC and is the Principal Investigator on the ONCOS-102 phase I trial in CPI refractory advanced melanoma. Dr. Shoushtari is a member of the research team of Dr. Jedd Wolchok, MD, PhD, Chief, Melanoma and Immunotherapeutics Service at the Memorial Sloan Kettering Cancer Center.

      For further information, please contact:

      Renate Birkeli
      Investor Relations
      Phone: +47-922-61-624
      Email: renate.birkeli@targovax.com

      Media and IR enquires:

      Andreas Tinglum - Corporate Communications (Norway)
      Phone: +47-9300-1773
      Email: andreas.tinglum@corpcom.no

      This information was brought to you by Cision http://news.cision.com

      https://news.cision.com/targovax/r/presentation-of-oncos-102-melanoma-data-at-sitc-annual-meeting,c2958264

      The following files are available for download:

      https://mb.cision.com/Public/17093/2958264/920422e203543ab4.pdf

      SITC presentation

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