NICE to Evaluate ENDOCUFF VISION®, a Medical Device to Help Detect Pre-Cancerous Polyps in Patients Undergoing Bowel Cancer Screening

LONDON, January 27, 2017 /PRNewswire/ --

Norgine B.V. today announced that the National Institute for Health and Care Excellence (NICE) is evaluating ENDOCUFF VISION^® through its Medical Technologies Evaluation Programme. The evaluation will provide guidance on the use of the device in colonoscopy in patients undergoing bowel cancer screening and surveillance. ^[1]

Norgine anticipates receiving final guidance in October 2017.

ENDOCUFF VISION^® is a Class I sterile medical device designed to attach to the end of the colonoscope that opens up the field of view by holding back colonic folds during colonoscope withdrawal. It is proven to significantly increase the detection of adenomas and polyps compared to standard colonoscopy.^[2]

Bowel cancer is the second most common cause of cancer-related mortality in the world ^[3], with nearly 1.4 million new cases diagnosed worldwide and 412,000 people in Europe. ^{[4], [5]} The detection and removal of pre-cancerous polyps during colonoscopy substantially reduces both the development of and death from colorectal cancer.^[6]

Bob Cuffe, General Manager UK & ROI, Norgine, commented "Norgine is confident that the use of ENDOCUFF VISION^® brings value to healthcare systems and patients by increasing the detection of cancerous polyps in patients undergoing bowel cancer screening and surveillance."

ENDOCUFF VISION^® is part of Norgine's colonoscopy portfolio which includes KLEAN-PREP^® and MOVIPREP^®.

ENDOCUFF VISION^® is available through Norgine's infrastructure in: Australia, Austria, Belgium, Finland, France, Denmark, Germany, Italy, Ireland, Netherlands, New Zealand, Norway, Portugal, Spain, Sweden, Switzerland and the UK.

In the US and Canada it is available through Olympus Corporation of the Americas.

To see how it works click here

View the full release on http://www.norgine.com

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1. Medical technology guidance scope: Endocuff Vision for endoscopic investigation. https://www.nice.org.uk/guidance/indevelopment/gid-mt509. [Accessed 26 January 2017]

2. Tsiamoulos et al. Gastrointestinal Endoscopy 2015;81(55) AB209. Abstract Sa 1423

3. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J et al.  Cancer incidence and mortality patterns in Europe:  Estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-1403

4. Colorectal Cancer Statistics, World Cancer Research Fund International, http://www.wcrf.org/int/cancer-facts-figures/data-specific-cancers/colorectal-cancer-statistics [Accessed 9 May 2015]

5. Zavoral M et al. Colorectal cancer screening in Europe. World J Gastroenterol 2009;15(47):5907-5915

6. LeClercq CMC, Bouwens MWE, Rondagh, EJA et al.  Postcolonoscopy colorectal cancers are preventable:  a population-based study.  Gut 2014;63:957-963