New Therapeutics Options in Huntington's Disease Pipeline as 45+ Key Companies are Working on Drug Profiles | DelveInsight

Huntington's Disease pipeline constitutes 45+ key companies continuously working towards developing 50+ Huntington's Disease treatment therapies, analyzes DelveInsight

LAS VEGAS, Oct. 24, 2022 /PRNewswire/ -- DelveInsight's 'Huntington's Disease Pipeline Insight – 2022' report provides comprehensive global coverage of available, marketed, and pipeline Huntington's disease therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Huntington's disease pipeline domain.

Key Takeaways from the Huntington's Disease Pipeline Report

• DelveInsight's Huntington's disease pipeline report depicts a robust space with 45+ active players working to develop 50 + pipeline therapies for Huntington's disease treatment. 
• Key Huntington's disease companies such as Prilenia Therapeutics, Ionis Pharmaceuticals, Annexon, Vaccinex, Neurocrine Biosciences, SAGE Therapeutics, PTC Therapeutics, WaVe life Sciences, Novartis, Neurimmune Therapeutics, SOLA Biosciences, UniQure Biopharma, Roche, Annexon, Inc., Azevan Pharmaceuticals, SOM Innovation Biotech SA, Asklepios BioPharmaceutical, Luye Pharma Group Ltd., BrainStorm Cell Therapeutics, Voyager Therapeutics, Passage Bio, Locana Bio, Ceptur Therapeutics, Enzerna Biosciences, AFFiRiS AG, Arvinas, Atalanta Therapeutics, Anima Biotech, and others are evaluating novel Huntington's disease treatment drugs candidate to improve the treatment landscape.
• Promising Huntington's disease pipeline therapies in various stages of development include Pridopidine, Tominersen, ANX-005, Pepinemab, Valbenazine, SAGE-718, PTC-518, WVE-003, AMT 130, Branaplam, NI-302, SOL-176, RO7234292, ANX005, SRX246, Bevantolol, SOM3355, BV-101 Gene Therapy, LPM3770164, Passage Bio Research Project, Huntington disease Research Project, BrainStorm Research Project, Locana Huntington disease Research Project,  Ceptur Huntington Research Project, HTT RNA Research project, mHTT Research Project, AFFiRiS Huntington Research Project, HTT Research Project, Anima Biotech mHTT Research Project, and others.
• In August 2022, Asklepios BioPharmaceutical, a wholly owned and independently operated subsidiary of Bayer AG,  received clearance to conduct a Phase I/II trial for its novel Huntington's Disease (HD) gene therapy, BV-101, in France through its subsidiary BrainVectis. This authorization, provided by the National Agency for Safety of Medicines and Health Products (ANSM), the country's governing drug authority, along with the approval of the trial protocol by the Ethics Committee in charge, enables the company to begin recruiting participants
• In March 2022, PTC Therapeutics announced the initiation of the PIVOT-HD Phase  II clinical trial evaluating PTC518 in people with Huntington's disease (HD). PIVOT-HD is a global trial starting in the United States. PTC518 is an oral, small molecule splicing modifier that was specifically designed to lower huntingtin mRNA and protein selectively. There are no current treatments for the underlying cause of HD
• In January 2022, Ionis Pharmaceuticals announced that its partner Roche is designing a new Phase II trial to evaluate tominersen in Huntington's disease (HD). After halting dosing in the Phase III GENERATION HD1 study, exploratory posthoc analyses suggest tominersen may benefit younger adult patients with lower disease burden. These results require confirmation in a randomized, placebo-controlled study
• In September 2021, Sage Therapeutics announced that the US Food and Drug Administration (FDA) has granted Fast Track Designation to SAGE-718 for development as a potential treatment for Huntington's disease (HD).
• In September 2021, Voyager Therapeutics introduced new programs in Huntington's disease, a monogenic form of ALS (SOD1), spinal muscular atrophy, and diseases linked to GBA1 mutations, all powered by its proprietary AAV capsids that have demonstrated superior transgene expression in the brain compared to AAV9 delivery in non-human primates.

Request a sample and discover the recent advances in Huntington's disease treatment @Huntington's Disease Pipeline Report

The Huntington's disease pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage Huntington's disease products, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the Huntington's disease pipeline landscape.

Huntington's Disease Overview

Huntington's disease is a rare, inherited disease that causes the progressive breakdown (degeneration) of brain nerve cells. It's an autosomal dominant condition caused by a single faulty gene on chromosome 4. The common symptoms of Huntington's disease include involuntary jerking or writhing movements (chorea), muscle problems such as rigidity or muscle contracture (dystonia), slow or abnormal eye movements, impaired balance, difficulty speaking or swallowing, difficulty organizing, prioritizing, or focusing on tasks, and fatigue and loss of energy. A general physical examination, medical history, and thorough neurological and psychiatric examinations are used for Huntington's disease diagnosis.

Huntington's disease treatment focuses on symptom management, which includes medications and psychotherapy. Tetrabenazine (Xenazine) and deutetrabenazine (Austedo) have been specifically approved by the FDA to suppress Huntington's disease-related involuntary jerking and writhing movements (chorea).

Find out more about Huntington's disease treatment @Drug Treatment for Huntington's Disease 

A snapshot of the Huntington's Disease Pipeline Drugs mentioned in the report:

Learn more about the emerging Huntington's disease pipeline therapies @Huntington's Disease Clinical Trials

Huntington's Disease Therapeutics Assessment

The Huntington's disease pipeline report proffers an integral view of Huntington's disease emerging novel therapies segmented by stage, product type,  molecule type,  mechanism of action, and route of administration.

Scope of the Huntington's Disease Pipeline Report 

• Coverage: Global 
• Therapeutic Assessment By Product Type: Mono, Combination, Mono/Combination
• Therapeutic Assessment By Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Therapeutics Assessment By Route of Administration:  Oral, Parenteral, Intravitreal, Subretinal, Topical
• Therapeutics Assessment By Molecule Type: Monoclonal Antibody, Peptides, Polymer, Small molecule, Gene therapy
• Therapeutics Assessment By Mechanism of Action: Dopamine D2 receptor antagonists, Glutamate modulators, Sigma-1 receptor agonists, HD protein inhibitors, RNA interference, Complement C1 inhibitors, CD100 antigen inhibitors, Vesicular monoamine transporter 2 inhibitors, P38 mitogen-activated protein kinase inhibitors, NMDA receptor modulators
• Key Huntington's Disease Companies: Prilenia Therapeutics, Ionis Pharmaceuticals, Annexon, Vaccinex, Neurocrine Biosciences, SAGE Therapeutics, PTC Therapeutics, WaVe life Sciences, Novartis, Neurimmune Therapeutics, SOLA Biosciences, UniQure Biopharma, Roche, Annexon, Inc., Azevan Pharmaceuticals, SOM Innovation Biotech SA, Asklepios BioPharmaceutical, Luye Pharma Group Ltd., BrainStorm Cell Therapeutics, Voyager Therapeutics, Passage Bio, Locana Bio, Ceptur Therapeutics, Enzerna Biosciences, AFFiRiS AG, Arvinas, Atalanta Therapeutics, Anima Biotech, and others
• Key Huntington's Disease Pipeline Therapies: Pridopidine, Tominersen, ANX-005, Pepinemab, Valbenazine, SAGE-718, PTC-518, WVE-003, AMT 130, Branaplam, NI-302, SOL-176, RO7234292, ANX005, SRX246, Bevantolol, SOM3355, BV-101 Gene Therapy, LPM3770164, Passage Bio Research Project, Huntington disease Research Project, BrainStorm Research Project, Locana Huntington disease Research Project,  Ceptur Huntington Research Project, HTT RNA Research project, mHTT Research Project, AFFiRiS Huntington Research Project, HTT Research Project, Anima Biotech mHTT Research Project, and others.

Dive deep into rich insights for FDA-approved drugs for Huntington's disease, visit @Huntington's Disease Drugs

Table of Contents

For further information on the Huntington's disease pipeline therapeutics, reach out @Drugs for Huntington's Disease

Related Reports

Huntington's Disease Market

Huntington's Disease Market Insights, Epidemiology, and Market Forecast – 2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key Huntington's disease companies including Amsterdam Molecular Therapeutics, Novartis, Retrotope, Hope Biosciences, Stealth BioTherapeutics, among others.

Huntington's Disease Epidemiology Forecast

Huntington's Disease Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted Huntington's disease epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

Wilson Disease Pipeline

Wilson Disease Pipeline Insight – 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Wilson disease companies, including Alexion Pharmaceuticals, Vivet Therapeutics, Orphalan, among others.

Wilson Disease Market

Wilson Disease Market Insights, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key Wilson disease companies, including Alexion Pharmaceuticals, Vivet Therapeutics, Orphalan, among others.

Bipolar Disorder Pipeline

Bipolar Disorder Pipeline Insight – 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key bipolar disorder companies, including Vanda Pharmaceuticals, Pear Therapeutics, Sunovion, Lyndra Therapeutics, among others.

Obsessive-Compulsive Disorder Pipeline

Obsessive-Compulsive Disorder Pipeline Insight – 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key obsessive-compulsive disorder companies, including Ceruvia Lifesciences, Biohaven Pharmaceuticals, Octapharma, among others.

Other Trending Reports

Goitre Market |  Thymus Cancer Market | US Healthcare Outlook Report | Venous Stenosis Market | Negative Pressure Wound Therapy Systems Market | Global Kinase Inhibitor in Autoimmune Diseases Market | Metrorrhagia Market | Dysfunctional Uterine Bleeding Market | Hypereosinophilic Syndrome Market | Age-related Vision Dysfunction Market | Dental Lasers Market | CRISPR Therapies Pipeline Insight | Cell And Gene Therapy For Multiple Myeloma Market | Drug Hypersensitivity Market | Dysthymia Market | Persistent Depressive Disorder Market | Cancer Vaccines Market | Weight Loss/Weight Management (Obesity) Market | Food Allergy Market | Obsessive-Compulsive Disorder Market | Tumor Ablation Market | Physiotherapy Equipment Market | Chimeric Antigen Receptor (CAR) T-Cell Therapy Market | Anti-hypertension Market | Radiofrequency Ablation Devices Market | Global Messenger RNA (mRNA)-based Vaccines and Therapeutics Market | Gastro Intestinal Bleeding Market | Trastuzumab Biosimilars Insight | Varicose Veins Market | Germ Cell Tumor Market | Intracardiac Echocardiography Devices Market | India Healthcare Report | Crows Feet Market | Seborrhoeic Dermatitis Market | Injectable Drug Delivery Devices Market | Structural Heart Devices Market | Substance (Drug) Abuse Market | Insulin Glargine Biosimilar Insight

Related Healthcare Blogs

Wilson Disease Treatment Outlook 

Bipolar Depression Therapeutics Pipeline 

About DelveInsight

DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. 

Connect with us at LinkedIn 

Contact Us

Shruti Thakur  
info@delveinsight.com 
+1(919)321-6187  
www.delveinsight.com

Logo: https://mma.prnewswire.com/media/1082265/DelveInsight_Logo.jpg