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Medigen's MVC-COV1901 Selected for WHO COVID-19 Solidarity Trial Vaccines

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News provided by

Medigen Vaccine Biologics Corporation

27 Oct, 2021, 02:35 GMT

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TAIPEI, Oct. 27, 2021 /PRNewswire/ -- Medigen Vaccine Biologics Corp (MVC) vaccine candidate, MVC-COV1901, has been recommended by an independent vaccine prioritisation advisory group to be included in the World Health Organisation (WHO) Solidarity Trial Vaccines (STv). Following the review of around 20 candidate vaccines by the external advisory group, MVC's vaccine was selected as one of two to be included in the global trial. 

The announcement by WHO, comes after the approval from WHO Ethics Review Committee and relevant regulatory authorities and ethics committees of Colombia, Mali and Philippines granted approval for the study to progress. Each clinical site and respective national principal investigators and research teams have begun recruiting volunteers to join the trial.

This is an international, randomized clinical trial platform designed to rapidly evaluate the efficacy and safety of promising new candidate vaccines contributing to the creation of a larger portfolio of vaccines needed to protect people from COVID-19 around the world.

MVC began developing its own vaccine in February of 2020 with the hopes of bringing forth a solution capable of helping in part end the devastating pandemic. MVC-COV1901 is a subunit vaccine with recombinant S-2P antigen adjuvanted with CpG 1018 supplied by Dynavax and aluminum hydroxide.

"We are extremely grateful that we have been selected to be part of the WHO International Solidarity Trial Vaccines against COVID-19. We have been working to design a vaccine that has mild side effects and actively protects the public from the adverse effects of the virus. Seeing promising results thus far, we hope that the international trial conducted by WHO and participating countries will assist to curb the escalation of cases," said Charles Chen, Vice Chairman & CEO, Medigen Vaccine Biologics Corp.

With the battle against the pandemic still on an incline, the need for effective vaccines is still in high demand and MVC believes it has the capacity, infrastructure, and expertise to contribute towards achieving global protection.

About MVC-COV1901

MVC-COV1901 is a subunit vaccine with recombinant S-2P antigen adjuvanted with CpG 1018 supplied by Dynavax and aluminum hydroxide. The S-2P antigen is a trimeric and prefusion-stable recombinant spike protein developed by the U.S. NIH. MVC has obtained a global technology license for S-2P from the U.S. Vaccine Research Center at National Institutes of Health (NIH).  Building upon the S-2P platform, MVC conducted large-scale screenings of various adjuvants and finalized the compositions of MVC-COV1901 vaccine to optimize safety and desired immunogenicity properties. MVC established the production platform of MVC-COV1901 and based on MVC's preclinical, Phase 1 and Phase 2 clinical study data, MVC-COV1901 has shown robust safety and promising immunogenicity responses and as a result applied and was granted EUA in Taiwan and continue to pursue global regulatory recognition.

About Medigen Vaccine Biologics Corp. (MVC)

MVC is a biopharmaceutical company using cell-based technologies to develop novel vaccines and biosimilars. With a goal of national self-sufficiency, MVC also aims to provide vaccines and biopharmaceuticals to meet regional needs and with a desire to help globally against the threats of infectious diseases. MVC's pipeline includes enterovirus EV71 vaccine, dengue vaccine, influenza quadrivalent vaccine which all have entered late clinical stage. MVC's large-scale production facility is state-of-the-art and adherent to international PIC/s GMP requirements. For more information, visit www.medigenvac.com.

WHO Media inquiries
mediainquiries@who.int

Medigen Contact:
Paul Torkehagen
Director, International Business Development
paul@medigenvac.com

Investor Relations:
ir@medigenvac.com

Medigen Media Enquiries:
Michelle Bridget, Continuum PR, on +6012 697 7356, or email michelle.bridget@continuumpr.com  

Logo - https://mma.prnewswire.com/media/1671127/MVC_Logo.jpg

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