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      Cytomegalovirus Infection Treatment Market elevates at a CAGR of 13.79% during 2020-2030, asserts DelveInsight

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      News provided by

      DelveInsight Business Research, LLP

      27 Jan, 2021, 15:00 GMT

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      - Cytomegalovirus Treatment Market size is anticipated to grow high due to an increased patient pool and robust pipeline candidates with novel mechanisms expected to intensify future competition

      LAS VEGAS, Jan. 27, 2021 /PRNewswire/ -- DelveInsight's "Cytomegalovirus (CMV) Infection Market Report" report provides an absolute comprehension of the Cytomegalovirus Infection, historical and forecasted epidemiology and the CMV market trends in the 7MM [the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan]. The Cytomegalovirus market report also proffers an analysis of recent Cytomegalovirus treatment practice/algorithm, market drivers, market barriers and unmet medical needs. 

      Some of the essential highlights of the Cytomegalovirus Therapeutics Market Research Report : 

      • Increasing CMV Infections cases in various regions leads to increased demand for advanced diagnostics that, in turn, contribute to the CMV market growth. 
      • The Cytomegalovirus Infection treatment market is divided into Prophylaxis and Therapeutic. Currently, the market is dominated by drugs like valganciclovir, valacyclovir hydrochloride, and others. However, the CMV market of these drugs will experience a plunge in market share due to the launch of new emerging therapies. 
      • Cytomegalovirus Therapeutics Market anticipates the emergence of pipeline products namely V160 (Merck), mRNA-1647 (ModernaTX), HB-101/VaxWave (Hookipa Biotech), Triplex (Helocyte), Maribavir (TAK-602) (Takeda/Shire Pharmaceuticals), and Viralym-M (AlloVir). 
      • One of the most promising anti-CMV drugs in clinical development is Maribavir (Shire). The drug is in phase III stage of development for the transplant cases with Cytomegalovirus Infections that are refractory or treatment-resistant, and also, for Cytomegalovirus (CMV) Infection Treatment in Hematopoietic Stem Cell Transplant Recipients.

      For additional information on Market Impact by Therapies, visit: Global Cytomegalovirus Treatment Market Report 

      Cytomegalovirus (CMV) Infection is a viral infection that rarely causes serious illness. Human CMV causes a broad variety of infection and illness in healthy adults, in those with compromised immune systems (such as AIDS), in those with cardiovascular disease, and in pregnant women who can pass the infection to their unborn child (congenital CMV). In 2020, the total of Cytomegalovirus diagnosed cases were found to be 111,959 cases in the 7MM. 

      The Cytomegalovirus Infection Market Report provides historical as well as forecasted epidemiological analysis segmented into: 

      • Total Diagnosed Cases of CMV Infection
      • Number of Infants born with Congenital CMV
      • CMV Patients among Hematopoietic Stem Cell Transplants (HSCT)
      • Number of CMV Patients among Solid Organ Transplantation (SOT)
      • Number of Refractory CMV Patients after HSCT/SOT
      • CMV Retinitis among HIV Patients

      Request for a free sample report for more insights @ CMV therapeutics market growth

      Cytomegalovirus Infection Therapeutics Market Analysis 

      The management of CMV infection is maintained by two approaches, i.e. prophylaxis and therapeutic approach. Currently, the global Cytomegalovirus treatment market is dominated by drugs like valganciclovir, valacyclovir hydrochloride, and others. However, the market of these drugs will experience a drop in the market share due to the launch of new emerging therapies. Recently, Prevymis (Letermovir) received FDA approval in 2017, to prevent Human Cytomegalovirus (HCMV) infection in transplant patients and entered the market in 2018. Prevymis covers a tiny targeted population because it is approved only for the prophylaxis of cytomegalovirus (CMV) reactivation and disease in adult CMV-seropositive recipients [R+] of an allogeneic hematopoietic stem cell transplant (HSCT). 

      Hence, it will positively impact the market size growth but will not be responsible for the major increase in the CMV market size. There is an estimated decline in its market after 2029, as the patent of prevymis will expire in 2029. Among the prophylactic potential market, two therapies, V160 and mRNA-1647, target the same patient population, CMV-seronegative and CMV-seropositive healthy adults (childbearing women) to prevent congenital CMV. Moreover, in the therapeutic potential market, it is believed that Maribavir can be a promising agent in the US for Cytomegalovirus Infection treatment.

      In the United States, antiviral drugs are used for CMV infection following transplant procedures. The drugs include valganciclovir, ganciclovir, cidofovir, foscarnet, or a combination. The US FDA and EMA support the CMV therapeutics pipeline by encouraging the drug development process through a different type of designations. 

      Cytomegalovirus Infection Emerging Products Along with Key Players 

      • Maribavir (TAK-602): Takeda/Shire Pharmaceuticals
      • ATA230: Atara Biotherapeutics
      • Triplex: Helocyte
      • Viralym-M: AlloVir
      • V160: Merck
      • VBI-1501: VBI Vaccines
      • HB-101 (VaxWave): Hookipa Biotech
      • AVX601: AlphaVax
      • CMV glycoprotein B MF59 (gB/MF59): Sanofi
      • ALVAC-CMV (vCP260): Sanofi
      • NPC-21: Nobelpharma
      • mRNA-1647: ModernaTX
      • VBI-1901: VBI Vaccines
      • ITI-1001: Immunomic Therapeutics 

      And several others. 

      Concluding Thoughts on CMV Therapeutics Market Growth 

      CMV Market Drivers are attributable to 

      • Emerging Therapies- The high burden of CMV disease and morbidity makes it a right candidate for new therapies and vaccines. 
      • Better Efficacy and Safety Profiles - Various pipeline molecules show better safety and promising activity than those currently being used. 
      • Increased incidence and prevalence - Increased public awareness creates a lucrative opportunity for innovation of therapeutics. 
      • Increased awareness - Growing R&D is increasing the demand for better diagnosis and CMV Infections treatment options. 

      However, there are  CMV Market size growth Barriers that influence CMV Market growth 

      • Challenges in existing therapies- Current therapies are inadequate because of severe toxicities.
      • Diagnostic challenges in congenital cytomegalovirus infection- Diagnostic options are much needed to improve the CMV prognosis and outcomes for patients, as existing diagnostic options do not detect some features of congenital CMV. 
      • Generic drugs of off-patent therapies- All available drugs for CMV infection have gone off-patented except one. The generic market of a drug shall affect the overall sales of the CMV market. 
      • The complex mechanism of action and treatment costs- There is a lack of knowledge about the complex mechanism of action of the disease with various targets for inhibition. 
      • Limitation in the current therapeutic market - One of the major unmet needs primarily in the prophylactic market is the efficacy and the viral resistance to the current drugs that is a limitation for the current therapeutic market. 

      Scope of the Cytomegalovirus Infection Market

      • Geography Covered: 7MM - The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), Japan.
      • Study Period: 3-year historical and 11-year forecasted analysis (2017-2030).
      • Cytomegalovirus Infection Markets Segmentation: By Geographies and By Cytomegalovirus Infection Therapies (Historical and Forecasted, Current and Upcoming)
      • Leading Companies investigating its candidates for CMV Infections: Takeda/Shire Pharmaceuticals, Atara Biotherapeutics, Helocyte, AlloVir, Merck, VBI Vaccines, Hookipa Biotech, AlphaVax, Sanofi, Nobelpharma, ModernaTX, Immunomic Therapeutics, and several others.
      • Analysis: Comparative and conjoint analysis of emerging therapies, Attribute Analysis.
      • Case Studies
      • KOL's Views
      • Analyst's View

      Request for a Webex demo of the report @ Cytomegalovirus (CMV) Infection Therapeutics Market 

      Table of Contents 

      1

      Key Insights

      2

      Executive Summary of Cytomegalovirus Infection

      3

      Cytomegalovirus Infection Market Overview at a Glance

      4

      Disease Background and Overview: Cytomegalovirus Infection (CMV)

      5

      Case Reports of Cytomegalovirus Infection

      6

      Cytomegalovirus Infection Patient Journey

      7

      CMV Epidemiology and Patient Population

      8

      Country Wise-Epidemiology of CMV Infections

      8.1

      United States

      8.2

      EU5 Countries

      8.2.1

      Germany

      8.2.2

      France

      8.2.3

      Italy

      8.2.4

      Spain

      8.2.5

      United Kingdom

      8.3

      Japan

      9

      Cytomegalovirus Infection Treatment Algorithm

      10

      Cytomegalovirus Infection Unmet Needs

      11

      Cytomegalovirus Infection Marketed Products

      11.1

      Valcyte: Roche

      11.2

      Foscavir: Clinigen Group plc

      11.3

      CytoGam: CSL Behring

      11.4

      Valtrex: GlaxoSmithKline

      11.5

      Vistide: Gilead Sciences

      11.6

      Prevymis: Merck & Co.

      11.7

      Cytotect CP: Biotest Pharma GmbH

      12

      Cytomegalovirus Infection Emerging Drugs

      12.1

      Key Cross Competition

      12.2

      CMV-Gyn (Cytotect 70): Biotest AG

      12.3

      Maribavir (TAK-602): Takeda/Shire Pharmaceuticals

      12.4

      ATA230: Atara Biotherapeutics

      12.5

      Triplex: Helocyte

      12.6

      Viralym-M: AlloVir

      12.7

      V160: Merck

      12.8

      VBI-1501: VBI Vaccines

      12.9

      HB-101 (VaxWave): Hookipa Biotech

      12.10

      AVX601: AlphaVax

      12.11

      CMV glycoprotein B MF59 (gB/MF59): Sanofi

      12.12

      ALVAC-CMV (vCP260): Sanofi

      12.13

      NPC-21: Nobelpharma

      12.14

      mRNA-1647: ModernaTX

      12.15

      VBI-1901: VBI Vaccines

      12.16

      ITI-1001: Immunomic Therapeutics

      13

      CMV Failed Therapies

      13.1

      ASP0113: Astellas Pharma Global Development, Inc.

      13.2

      Brincidofovir: Chimerix Inc.

      13.3

      CSJ148: Novartis (Development suspended)

      14

      Cytomegalovirus Infection 7MM Analysis

      15

      CMV Attribute Analysis of Prophylactic Drugs

      16

      Cytomegalovirus Infection Attribute Analysis of Therapeutic Drugs

      17

      Key Market Forecast Assumptions

      18

      The United States Cytomegalovirus Infection Market Outlook

      19

      EU-5 Countries CMV Market Outlook

      19.1

      Germany Market Size

      19.2

      France Market Size

      19.3

      Italy Market Size

      19.4

      Spain Market Size

      19.5

      United Kingdom Market Size

      20

      Japan Cytomegalovirus Infection Market Outlook

      21

      Cytomegalovirus Infection Market Drivers

      22

      CMV Market Barriers

      23

      Cytomegalovirus Infection SWOT Analysis

      24

      Reimbursement and CMV Market Access

      25

      Recognized Establishments

      26

      Appendix

      27

      DelveInsight Capabilities

      28

      Disclaimer

      29

      About DelveInsight

      Browse detailed TOC with charts, figures, tables @ Cytomegalovirus Infection Market Size Report

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      • Cytomegalovirus (CMV) Infection Epidemiology Forecast Analysis 

      DelveInsight's Cytomegalovirus (CMV) Infection - Epidemiology Forecast 2030 report delivers an in-depth understanding of the disease, historical, and forecasted epidemiology of Cytomegalovirus (CMV) Infection in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

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      Cytomegalovirus (CMV) Infection Pipeline Insight, 2020 report by DelveInsight outlays comprehensive insights of present clinical development scenario and growth prospects across the Cytomegalovirus (CMV) Infection market. 

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      DelveInsight

      DelveInsight is a leading Business Consultant, and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing end to end comprehensive solutions to improve their performance.

      Contact us:

      Shruti Thakur
      info@delveinsight.com
      +1(919)321-6187 
      DelveInsight

      Logo: https://mma.prnewswire.com/media/1082265/DelveInsight_Logo.jpg

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