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Treatment Pipeline for COPD Fails to Address Many Unmet Needs, Says GBI Research


News provided by

GBI Research

19 Jan, 2016, 13:00 GMT

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LONDON, January 19, 2016 /PRNewswire/ --

The Chronic Obstructive Pulmonary Disease (COPD) treatment pipeline lacks innovation despite an influx of new therapies, says GBI Research.

Analysis from business intelligence provider GBI Research - Frontier Pharma: Chronic Obstructive Pulmonary Disease (COPD) - Identifying and Commercializing First-in-Class Innovation - states that while currently-available drugs aim to manage the frequency and severity of symptoms associated with COPD, none have been shown to modify long-term disease progression.

In addition to the need for disease-modifying drugs, much of the unmet need associated with COPD has been linked to poor adherence to medication. For a complimentary sample of this research, please visit the GBI Research website.

Senior Analyst Yasser Mushtaq: "Tedious drug delivery processes and the need for frequent daily doses ultimately lead to poor compliance and management of COPD symptoms. As a consequence, drug development programs are focusing on developing long-acting medication.

"There is also a need for alternative anti-inflammatory agents. Traditionally reliant on Inhaled Corticosteroids (ICS), analysis of the COPD product development pipeline has confirmed greater interest in novel anti-inflammatory agents."

The analyst adds that beyond ICS therapy, the current market offers very limited anti-inflammatory treatment, which is a notable unmet need in COPD.

GBI Research's report also states that first-in-class product development in COPD treatment constitutes only 16.5% of the pipeline, which is relatively small compared to other respiratory indications. For example, asthma therapeutics exhibit greater innovation, with first-in-class products making up 23% of the pipeline.

Mushtaq continues: "There are suggestions that such innovation is filtering through into the COPD therapeutics pipeline, as asthma and COPD share mechanisms of pathophysiology, making it likely that products will be applicable to both diseases.

"In this way, innovations in the asthma treatment pipeline will significantly aid that of COPD. However, there is no clear indication that disease-modifying drugs will be released onto the COPD market any time soon, making it an attractive proposition for major pharma players."

About GBI Research 

GBI Research is a leading provider of business intelligence reports, offering actionable data and forecasts based on the insights of key healthcare industry influencers to ensure you stay up-to-date with the latest market trends.

For the full range of market-leading analysis on the pharmaceutical industry, visit GBI Research's report store.

Follow GBI Research online for the latest healthcare industry updates:

Facebook | LinkedIn | Twitter

For more information, please contact GBI Research on: +44-161-359-5817

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