The Menarini Group, an Italian biopharmaceutical company present in 136 countries worldwide, and Melinta Therapeutics, a US company dedicated to the discovery, development and commercialization of novel antibiotics to treat serious bacterial infections, have announced an agreement under which Menarini will acquire the exclusive rights to commercialize meropenem/vaborbactam (Vabomere[TM] in the US), oritavancin (Orbactiv®) and minocycline IV (Minocin IV®) in 68 countries in Europe, in Asia-Pacific including China, South Korea, and Australia (Japan excluded), and in the Commonwealth of Independent States (CIS) including Russia.
This agreement builds on Melinta and Menarini's existing commercial and co-development agreement for delafloxacin - announced in 2017 - in the same 68 markets.
"We are excited to expand our partnership with the Menarini Group and significantly increase global access to our dynamic antibiotic portfolio," said Dan Wechsler, President and CEO of Melinta.
"We at Menarini welcome this opportunity to continue our collaboration with Melinta which will further strengthen our presence in the infectious disease market," declared Pio Mei, General Manager of the Menarini Group. "The addition of meropenem/vaborbactam, oritavancin and minocycline IV to our current portfolio bolsters our high-value antibiotic platform in support of our mission, "Infection in Focus," aimed at fighting life-threatening bacterial diseases which are an increasing global concern."
The marketing authorization application for meropenem/vaborbactam is currently under review by EMA. On 20 September 2018, the Committee for Medicinal Products for Human Use (CHMP) expressed its positive opinion, recommending the granting of a marketing authorisation for the medicinal product intended for the treatment of complicated intra-abdominal and urinary tract infections, hospital-acquired pneumonia, bacteraemia that occurs in association with any of these infections and infections due to aerobic gram-negative organisms where treatment options are limited. Orbactiv, a long acting lipoglycopeptide, has been approved by EMA in the treatment of adults with acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible designated gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
The Menarini Group is an Italian pharmaceutical company with a turnover of 3.6 billion Euro and 17,029 employees. With 16 manufacturing sites and 7 R&D centers, Menarini has a strong presence in 136 countries.