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The Medicines Patent Pool Expands Mandate to Hepatitis C and Tuberculosis Treatment


News provided by

Medicines Patent Pool

06 Nov, 2015, 11:57 GMT

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Medicines Patent Pool (PRNewsFoto/Medicines Patent Pool) (PRNewsFoto/Medicines Patent Pool)

GENEVA, November 6, 2015 /PRNewswire/ --

MPP's voluntary licensing work could benefit millions of patients in low- and middle-income countries  

The Medicines Patent Pool (MPP), the world's only voluntary licensing mechanism in public health, announced an expansion of its mandate today to hepatitis C and tuberculosis medicines. The UNITAID Executive Board, meeting November 4-5 in Geneva, approved the MPP's proposals to improve access to both life-saving direct acting antivirals (DAAs) to treat hepatitis C and new and re-purposed medicines for tuberculosis. UNITAID created the MPP in 2010 to provide better health options for people living with HIV. To date, MPP has signed agreements for 12 antiretrovirals (ARVs) for countries home to 87-93% of people living with HIV in the developing world.

     (Logo: http://photos.prnewswire.com/prnh/20151106/284566LOGO )

"I greatly welcome the broadening of the Medicines Patent Pool's mandate to encompass hepatitis C and tuberculosis, giving MPP a vital opportunity to help secure lower prices for medicines to fight these two lethal diseases," said Philippe Douste-Blazy, Chair of the Executive Board at UNITAID.

"The MPP is a cornerstone of UNITAID's efforts to transform the HIV medicines market and rapidly scale up HIV treatment in low- and middle-income countries," said Lelio Marmora, UNITAID's Executive Director. "The MPP now joins us in helping to meet international targets to make curative hepatitis C and TB medicines accessible to those who need them."

The World Health Organization estimates that hepatitis C (HCV) affects between 130 and 150 million people worldwide. The vast majority lives in low- and middle-income countries. New direct acting antivirals that are effective across all major HCV strains could cure millions. Building on its HIV model, the MPP will seek to license for generic manufacture new and pipeline hepatitis C medicines that can eliminate the virus in a short course of oral therapy.

"The recent approval of new treatments with greater efficacy and low side effects represents an incredible opportunity to move closer to eradication, but only if these drugs are affordable and accessible," said Raquel Peck, CEO for the World Hepatitis Alliance, an umbrella organisation representing 400 million patients. "We have urged for the Medicines Patent Pool's participation in the HCV response and are thrilled with the UNITAID board decision."

Tuberculosis is the leading cause of death for people living with HIV and killed 1.5 million people globally in 2014 alone. TB treatment has become more complex, particularly with the emergence of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis. The MPP will work to ensure access to new treatments for multi-resistant and drug-susceptible TB.

"The TB Alliance welcomes the MPP's entry into the TB field," said Mel Spigelman, President & CEO of the Global Alliance for TB Drug Development, the world's leading product development partnership (PDP) for the development of TB medicines. "We are looking forward to working with the MPP on a range of projects, from access-oriented licensing for new drugs and regimens, to the development of appropriate formulations for children."

"We thank UNITAID for its confidence in the MPP," said Greg Perry, MPP's Executive Director. "MPP believes that its unique approach to negotiating licences for HIV is working and we look forward to applying our model to tackling access and innovation challenges in HCV and TB."

New numbers released today confirm that the MPP has saved the international community $119.6 million from the procurement of low-cost HIV medicines, and its generic partners have distributed 7.26 million patient-years of treatments. The organisation is working on more than 50 development projects to bring MPP-licensed HIV antiretrovirals to market. These antiretrovirals include new promising treatments as well as WHO-recommended HIV medicines for first and second-line treatment for adults and children of all age groups.

About the Medicines Patent Pool (MPP) 

The Medicines Patent Pool is a United Nations-backed organisation offering a public-health driven business model that aims to lower the prices of HIV medicines and facilitate the development of better-adapted HIV treatment, such as simplified "fixed-dose combinations" (FDCs) and special formulations for children, through voluntary licensing and patent pooling.  Founded and fully funded by UNITAID, the MPP works with a range of stakeholders - communities of people living with HIV, civil society, governments, industry and international organisations. To date, the MPP has signed agreements for twelve antiretrovirals with six patent holders and is working with 14 manufacturers on more than 50 projects to develop HIV-licensed medicines.

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