TUCSON, Arizona, April 12, 2017 /PRNewswire/ --
- Prostate cancer accounts for 15 percent of all cancers diagnosed in men3
- Elevated expression of p504s has become a useful biomarker in the diagnosis of prostate adenocarcinoma1
- Roche's anti-p504s (SP116) Primary Antibody is an important tool to aid clinicians in making a more accurate diagnosis with a smaller tissue sample
Roche (SIX: RO, ROG; OTCQX:RHHBY) today announced the global launch of the anti-p504s (SP116) Rabbit Monoclonal Primary Antibody2 for prostate cancer diagnosis. This antibody has been validated for use in a dual stain with the VENTANA Basal Cell Cocktail (34ßE12+p63) to aid in distinguishing morphologically difficult cases as benign, atypical or cancerous on a single slide. The assay is an in vitro diagnostic (IVD) primary antibody for use on the VENTANA BenchMark IHC/ISH series of automated slide stainers.
Elevated expression of p504s – also known as α-methylacyl-CoA racemase (AMACR) – has become a useful biomarker in the diagnosis of prostate adenocarcinoma1. When this biomarker is used in a dual stain with the VENTANA Basal Cell Cocktail (34ßE12+p63) it can reduce the need for multiple slides to make a diagnosis. This can be critical when limited tissue sample is available, as is often the case with prostate biopsies.
"As the second most common cancer in men, prostate cancer is a serious public health concern," said Ann Costello, Head of Roche Tissue Diagnostics. "The anti-p504s (SP116) Primary Antibody is an important tool to aid clinicians in making a more accurate diagnosis with a smaller tissue sample."
An estimated 1.1 million men worldwide were diagnosed with prostate cancer in 2012, accounting for 15 percent of all cancers diagnosed in men3. The anti-p504s (SP116) Rabbit Monoclonal Primary Antibody enhances the Roche prostate portfolio of key assays used to diagnose prostate cancer.
1 Jiang Z, Woda BA, Rock KL, et al. P504S: a new molecular marker for the detection of prostate carcinoma. Am. J. Surg. Pathol. 2001;25:1397-1404.
2 This antibody is intended for in vitro diagnostic (IVD) use. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information and proper controls.
3 Globocan. Cancer Fact Sheets: Prostate Cancer. Globocan website. http://globocan.iarc.fr/old/FactSheets/cancers/prostate-new.asp
About the anti-p504s (SP116) Rabbit Monoclonal Primary Antibody
Anti-p504s (SP116) Rabbit Monoclonal Primary Antibody is intended for laboratory use in the detection of α-methylacyl-CoA racemase (AMACR) in sections of formalin-fixed, paraffin-embedded (FFPE) tissue. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information and proper controls. This antibody is intended for in vitro diagnostic (IVD) use.
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Roche Tissue Diagnostics Media Relations
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