Global Circulating Tumor Cell (CTC) Diagnostics Strategic Market Report 2015-2022 - Research and Markets

DUBLIN, April 03, 2017 /PRNewswire/ --

Research and Markets has announced the addition of the "Circulating Tumor Cell (CTC) Diagnostics - Global Strategic Business Report" report to their offering.

This report analyzes the worldwide markets for Circulating Tumor Cell (CTC) Diagnostics in US$. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Rest of World.

Annual estimates and forecasts are provided for the period 2015 through 2022. Also, a six-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs.

The report profiles 48 companies including many key and niche players such as

• ApoCell, Inc. (US)
• Biocep Ltd. (Israel)
• Biocept, Inc. (US)
• Biofluidica Microtechnologies LLC (US)
• Celltraffix Inc. (US)
• Clearbridge Biomedics (Singapore)
• Creatv Microtech, Inc. (US)
• Cynvenio Biosystems, Inc. (US)
• Epic Biosciences Inc. (US)
• Fluxion Biosciences, Inc. (US)
• Ikonisys, Inc. (US)
• IVDiagnostics, Inc. (US)
• Janssen Diagnostics LLC (US)
• QIAGEN Hannover GmbH (Germany)
• RARECELLS SAS (Italy)
• ScreenCell (France)
• STEMCELL Technologies, Inc. (Canada)

Key Topics Covered:

1. Industry overview

Market Outlook
Clinical Relevance of CTCs
CTC Detection
Real-Time Liquid Biopsy' Scores Over Surgical Biopsy
Major Challenges in CTC Diagnostics
Need for CTC Enrichment and Popular Methods
CTC Enrichment Techniques
Select Available CTC Detection Technologies
Select CTC Isolation Systems
A Brief Comparison
CTC Identification
Various Approaches
CTC Identification Approaches
List of mRNA Markers for RT-PCR-based Detection of CTCs by Tumor Type
CellSearch System
The First FDA Approved Automated Enrichment/Isolation Technique
Rising Incidence of Cancer
An Opportunity Indicator

2. Market trends and drivers

Liquid Biopsy: the New Buzzword in Healthcare
Select Companies Active in Cancer Liquid Biopsy
CTCs for Personalized Cancer Treatment
Microfluidic Chip-based Technologies
A Promising Avenue for Cancer Diagnosis
CTC Microdevices Hog the Limelight
Increasing Research Reveal Further Complexities to CTC Composition and Behavior
EpCAM Glycoprotein
Insufficient for CTC Detection
New Isolation Techniques Show Promise in Detecting EpCAM- Negative CTCs
Physical Property-based Enrichment Technologies Lose Fizz
Evidence in Favor CTC Heterogeneity Gains Strength
CTC Clusters Raise Research Interest
Detection of EMTs Gains Precedence in the Backdrop of Recent Research Findings
Limitations of CTC Technology for Point-of- Care Testing
CTC Technologies Offer an Edge over Imaging Tests for Breast Cancer Prognosis
Limited Biomarkers Utilized In CTC Diagnostics
A Threat to Market Growth?
Select Research Findings in Recent Years
Microfluidic Device with Micro-Hall Sensors Detect CTCs with Higher Sensitivity and Specificity
NBiomics Makes its Contribution to CTC Diagnosis
Researchers at University of Michigan Develop Revolutionary Capture CTCs Method
Dean Flow Fractionation to Overcome Limitations Associated with Conventional Biomarker Analysis
Gold Nanoparticles Help in the Detection of CTCs

3. Medical diagnostics market - a conceptual overview

Clinical Diagnostics
Table 4: Leading Players in the Global In Vitro Diagnostics (IVD) Market (2013)
Market Share Breakdown by Value Sales for Roche Diagnostics, Abbott Laboratories, Siemens, J&J, Beckman Coulter, bioMerieux, and Others (includes corresponding Graph/Chart)
Table 5: Global In-Vitro Diagnostics (IVD) Market (2013): Percentage Breakdown for Value Sales by Segment for Point of Care, Immunity Tests, Clinical Chemistry, Nucleic Acid Tests, Histology/Cytology, Microbiology, Haematology and Others (includes corresponding Graph/Chart)
Molecular Diagnostics
Growth Drivers
Molecular Diagnostics for Lymphoid Malignancies
Market Trends & Issues
Global Molecular Diagnostics on a High Growth Curve
Automation Driving Global Market
Molecular Diagnostics: Marking Convergence of Numerous Technologies
Aging Population, Disease Incidence
Fundamental Drivers of Growth
Pharmaceutical Firms Carving their Niche in the Molecular Diagnostics Market
Limited Reimbursements by Third Party Payers
A Stumbling Block
Molecular Diagnostics and Intellectual Property
Business Opportunities in the Offing
Medical Training and Practice Challenges
Hurdles All the Way for Companies Eyeing Molecular Diagnostics
Integration of Molecular Diagnostics into Therapeutics
Molecular Diagnostics
Moving from Centralization to Decentralization

4. Circulating tumor cell (CTC) diagnostics - enrichment, identification and characterization methods

Introduction
Enrichment
Filtration (iSET)
Density Gradient
Immuno-magnetic Cell Enrichment
Advantages of Different CTC Enrichment Procedures
AdnaTest
Identification
1. PCR-Based Analysis
Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
RT-qPCR
2. Cytometric Methods
Fiber-Optic Array Scanning Technology (FAST)
Laser Scanning Cytometry (LSC)
Flow Cytometry
CellSearch
Maintrac®
CTC-Chip
Enzyme-linked Epithelial Immunospot Assay (ELISPOT)
Fluorescence In Situ Hybridization (FISH)
Vita-Assay®
TelomeScan
CytoTrack
Some Other Methods for Detection of CTCs
Characterization
Chemo-Sensitivity Testing of CTCs

5. Product launches and introductions

Vortex Biosciences Launches VTX-1 Liquid Biopsy System
Vortex Biosciences Secures CE Mark and FDA Class I Registration for VTX-1 Liquid Biopsy System
Fluxion Biosciences Roll Out New CTC Recovery Kits
Biocept Launches c-MET Amplification Detection Test
Biocept Launches ROS1 Test for Identifying Suitable Therapeutic Targets for NSCLC

6. Recent industry activity

Menarini-Silicon Inks Agreement to Take Over CELLSEARCH® CTC Assets
Cancer Genetics and ApoCell Team Up for Cancer Profiling and Therapy Selection
Genomic Health Signs Commercial Agreement with Epic Sciences for AR-V7 Liquid Biopsy Test
BGI Joins Hands with Clearbridge BioMedics to Market CTC Products in China
Abnova Secures License to CSV Monoclonal Antibody for CTC Detection
Sorrento Secures License to CytoLumina's NanoVelcro CTC Profiling Assay
Janssen Announces Utility of CELLSEARCH® System in PD-L1 Expression Detection on CTCs
Qiagen Acquires AdnaGen's CTC Enrichment Technology
Tokai Inks Deal with Qiagen for Licensing CTC Enrichment Technology
ScreenCell Enters Collaborative Study for Evaluating CTC Enrichment Capability of ScreenCell Products

7. Focus on select players

8. Global market perspective

Total Companies Profiled: 48

- The United States (31)
- Canada (3)
- Europe (10)
- France (1)
- Germany (6)
- The United Kingdom (2)
- Italy (1)
- Asia-Pacific (Excluding Japan) (3)
- Middle East (1)

For more information about this report visit http://www.researchandmarkets.com/research/3ztlz6/circulating_tumor

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