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GammaPod revolutionizes breast cancer treatment: Italy introduces high-dose stereotactic radiotherapy in a single session to Europe

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News provided by

Tema Sinergie SpA

29 Apr, 2025, 09:14 GMT

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A new technology marks a turning point in the treatment of early-stage breast cancer

FAENZA, Italy, April 29, 2025 /PRNewswire/ -- GammaPod, one of the most advanced innovations in the treatment of breast cancer, officially arrives in Europe thanks to the commitment of Tema Sinergie SpA, an Italian company based in Faenza. With 40 years of experience in the healthcare sector, Tema Sinergie continues to be a benchmark for introducing innovative oncology solutions. The GammaPod system, invented by physicist Cedric Yu, Professor Emeritus at the University of Maryland (USA) and produced by Xcision Medical Systems, a U.S.-based company founded by Yu himself, was proudly introduced by Tema Sinergie to the European continent, installing the first system at the "Santa Maria della Misericordia" Hospital in Udine, and more set to begin treating patients soon.

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With GammaPod™, radiation oncologists can be at the forefront of a new era in cancer care by providing Stereotactic Partial Breast Irradiation (S-PBI), an advanced type of SBRT, for breast cancer. The delivery of higher doses in one or several large fractions differentiates stereotactic radiotherapy from conventional techniques. Born out of the vision to extend the dosimetric benefits of stereotactic radiotherapy to patients undergoing breast conserving treatment, GammaPod™ is a new precision tool with the potential to change the way early stage breast cancer is managed.

GammaPod represents a true revolution in the treatment of breast cancer: it allows the safe and precise administration of high doses of radiation to the tumor because, unlike conventional radiotherapy equipment, designed to treat tumors in all areas of the body, GammaPod was invented and designed to treat only breast cancer. For this reason, it is able to concentrate the entire dose on the tumor alone, drastically reducing exposure and damage to surrounding healthy tissue, thus minimizing side effects. This allows the tumor to be treated with a much higher dose of radiation until it is destroyed, in a single fraction.

This non-invasive, single-fraction approach, replacing the numerous fractions used with conventional equipment, offers patients a rapid therapeutic path with obvious benefits also in terms of quality of life.

The clinical study conducted at the hospital in Udine was recently published in the prestigious Red Journal (International Journal of Radiation Oncology, Biology, Physics) which demonstrated that GammaPod is safe and effective in the pre-operative treatment of breast cancer, with a significant reduction in the cell proliferation index (Ki-67), an important marker for evaluating the tumour response to radiotherapy.

"The results are extraordinary," says Dr. Marco Trovò, Director of Radiotherapy at the Udine hospital. "GammaPod allows us to administer a very high dose of radiation in a single session, with a clear biological response, as indicated by the drop in Ki-67."

On May 5, 2025, GammaPod will be the star of the Satellite Symposium "Reducing the Impact of Breast Cancer," organized by Tema Sinergie during the ESTRO 2025 congress in Vienna. The session will feature international experts, including Prof. Cedric Yu, who will delve into the technology's features, Prof. Asal Rahimi and Dr. Marco Trovò, who will present the results of their respective clinical studies. The symposium will be moderated by Prof. Philip Poortmans and Prof. Icro Meattini.

Tema Sinergie's commitment to introduce this technology in Europe underscores the importance of international collaboration in bringing new patient care solutions to the market. With this commitment, GammaPod is set to become a key pillar in the fight against breast cancer worldwide.

Gammapod
https://www.gammapod.eu

Article
https://www.redjournal.org/article/S0360-3016(25)00152-X/abstract

Tema Sinergie
https://www.temasinergie.com

Video - https://mma.prnewswire.com/media/2673502/Tema_Sinergie_GammaPod.mp4
Logo - https://mma.prnewswire.com/media/2673488/Tema_Sinergie_Logo.jpg

Media contact:
Stefano Camanzi
marketing@temasinergie.com
+39 0546 622 663

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