DUBLIN, November 23, 2017 /PRNewswire/ --

The "Cell Line Characterization Services Market, 2017-2027" report has been added to Research and Markets' offering.

The Cell Line Characterization Services Market, 2017-2027' report features a comprehensive view on the current market landscape and future outlook of testing and/or authentication services for the characterization of cell lines. The report provides information on organizations that offer contract services for the characterization of cell lines.

Cross contamination and cell line misidentification are some of the major concerns associated with the use of cell lines. According to published literature, cell lines used for scientific experiments are either misidentified or contaminated in approximately 15-25% cases. The use of such cell lines yields unreliable and irreproducible results, and leads to significant delays in research time lines and financial losses. The detrimental impact of using incorrect/misidentified cell lines poses a significant burden on the global healthcare budget

It has been estimated that a net loss of USD 28 billion is incurred every year on research that cannot be replicated due to the involvement of misidentified or contaminated cell lines in the US. Therefore, it is crucial to properly identify and authenticate cell lines used for research, both at the start of a project, as well as during the course of the study. To carry out cell line characterization, factors such as source of cell lines, their development history and the biological properties of cells determine the analytical tests required for characterization.

It is also worth highlighting that several regulatory authorities and scientific communities have undertaken different initiatives to spread awareness on the importance of cell line characterization. Various rules and standards have also been formulated, making it mandatory to characterize cell lines while submitting applications for marketing authorization, for receipt of grants/funds, or for publishing cell-based research in leading journals.

Key Topics Covered:

1. PREFACE

2. EXECUTIVE SUMMARY

3. INTRODUCTION

• Introduction to Cell Culture and Cell Lines
• Cell Banks
• Cell Line Characterization
• Outsourcing of Cell Line Characterization Services

4. CELL LINE AUTHENTICATION

• Need for Cell Line Authentication
• Cell Line Authentication: Historical Timeline
• Cell Line Authentication: Role of American Type Culture Collection (ATCC)
• Cell Line Authentication: Role of International Cell Line Authentication Committee (ICLAC)
• Cell Line Authentication: Role of Global Biological Standards Institute (GBSI)
• Factors Contributing to Cell Line Misidentification
• Awareness Surveys
• STR Profiling Kits
• Cell Line Authentication: Competitive Landscape

5. REGULATORY RECOMMENDATIONS AND GUIDELINES

• Guidelines Issued by International Regulatory Agencies
• Regulatory Guidelines for Cell Line Characterization in the US
• Regulatory Guidelines for Cell Line Characterization in Europe
• Regulatory Guidelines for Cell Line Characterization in Japan

6. COMPETITIVE LANDSCAPE

• Cell Line Characterization Service Providers: Market Landscape (Industry Players)
• Cell Line Characterization Service Providers: Market Landscape (Non-Industry Players)
• Cell Line Characterization Service Providers: Most Prominent Hubs

7. BIOREPOSITORIES

• American Type Culture Collection
• Coriell Institute for Medical Research
• European Collection of Authenticated Cell Cultures
• DSMZ

8. COMPANY PROFILES

• BioReliance (a Part of SAFC Commercial)
• Charles River Laboratories (CRL)
• Cell Line Genetics
• Eurofins Scientific
• Molecular Diagnostic Services
• SGS
• Avance Biosciences
• Biomeva (Acquired by AGC)
• Creative Bioarray
• Livogen Pharmed
• MTI-GlobalStem (a Part of Thermo Fisher Scientific)
• TFBS Bioscience
• Waisman Biomanufacturing
• WuXi AppTec
• Other Players

9. MARKET OPPORTUNITY AND SIZING

• Forecast Methodology
• Input Data Tables and Assumptions
• Cell Line Characterization Services Market Outlook, 2017-2027

10. KEY INSIGHTS

• Cell Line Characterization Service Providers: Regional Analysis
• Cell Line Characterization Service Providers: Heat Map Analysis (Industry Players)
• Cell Line Characterization Services: Spin Wheel Analysis (Industry Players)

11. CONCLUSION

• Mishandling and Cross Contamination are the Root Causes of Cell Line Misidentification
• Several Initiatives have been Launched by Various Organizations to Overcome such Challenges Associated with Cell Line Related R&D
• Most Service Providers in this Domain Offer Services for the Characterization of Mammalian Cell Lines
• STR Profiling is Considered to be the Current Gold Standard for Authentication of Cell Lines
• Several Contract Service Providers have Added Significant Value Within this Market by Providing High-Quality Cell Line Characterization and Authentication Solutions
• The Market Landscape Features a Mix of Both Industry and Non-Industry Players; the US and Europe are the Most Active Regional Hubs
• Fostered by the Increased Demand for Cell Lines in Life Science Research, the Market is Likely to Witness Steady Growth in the Coming Decade

12. INTERVIEW TRANSCRIPTS

• Fan Chen, Vice President BioProcessing, LakePharma
• Michael Pointek, Managing Director, ARTES Biotechnology
• Nienke Smits, Business Development, ModiQuest
• Oscar Hoogteijling, Business Development Manager, Bioceros

13. APPENDIX 1: TABULATED DATA

14. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

• AbbVie
• ABS
• Acambis
• Accelero Bioanalytics
• Actlabs
• Affymetrix
• Agilent Technologies
• Agilux Laboratories
• Alphora Research
• Ambry Genetics
• American National Standards Institute
• American Type Culture Collection
• Amgen
• Applied Biological Materials (abm)
• Applied Genetics Laboratories
• Applied Genomics Technology Center (AGTC), Wayne State University
• Applied StemCell (ASC)
• ARTES Biotechnology
• Australian Genome Research Facility
• Avance Biosciences
• BaseClear
• BEX
• Bioceros
• BioCrystal
• BIO-ENGINEERING
• Biogen
• BioMaxLab
• Biomay
• Biomedical Core Facility, Rappaport Faculty of Medicine, Technion Israel Institute of Technology
• BIOMEVA
• Bionique Testing Laboratories
• BioOutsource (now part of Sartorius Stedim Biotech Group)
• Biopolymer/Genomics Core Facility, University of Maryland
• Biopremier
• BioReliance
• Bio-Synthesis
• Biovian
• Blue Stream Laboratories
• Cancer Research UK Cambridge Institute (CRUK CI)
• Cedars Sinai
• Cell Culture
• Cell Culture and Cytogenetics Facility, University of Pittsburgh
• Cell Guidance Systems
• Cell Line Genetics
• Cellaria
• CellBank Australia
• Cellonex
• Celsis International
• Center for Genetic Medicine (CGM), Northwestern Medicine
• Center for Genomic Medicine, National Cheng Kung University
• Central Illinois Grain Inspection
• Characterized Cell Line Core Facility, MD Anderson Cancer Center, The University of Texas
• Charles River Laboratories
• Clean Cells
• CLS Cell Line Service
• Coriell Institute for Medical Research
• Cosmo Genetech
• Covance
• Creative Bioarray (a division of Creative Dynamics)
• Cybrdi
• Cytogenetics Research Core Laboratory, OHSU
• DDC Medical (a division of DNA Diagnostics Center)
• Department of Immunology, Genetics and Pathology, Uppsala University
• Department of Molecular & Cell Biology (MCB), University of California
• Department of Molecular Medicine (MOMA), Aarhus University Hospital
• Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health
• DiagCor Bioscience
• Diagnostic Cytogenetics
• DNA Analysis Facility on Science Hill, Yale University
• DNA Core Facility, University of Missouri
• DNA Data Bank of Japan
• DNA Forensics Laboratory
• DNA Sequencing Core Facility, University of Utah
• DNA Sequencing Facility, Perelman School of Medicine, University of Pennsylvania
• DNA Sequencing Facility, The University of Manchester
• DNA True Test
• Drug Screening Rendered
• Duke Clinical and Translational Science Institute, Duke University
• Eli Lilly
• Endeavour DNA
• EuBiologics
• Eurofins Genomics
• Eurofins Lancaster Laboratories
• Eurofins Sinensis
• European Directorate for the Quality of Medicines and HealthCare (EDQM)
• European Medicines Agency
• European Molecular Biology Laboratory
• Friedrich-Loeffler-Institute
• Garvan Institute of Medical Research
• Gates Center for Regenerative Medicine, University of Colorado
• Genentech
• GENERI BIOTECH
• Genetic Resources Core Facility (GRCF), Johns Hopkins School of Medicine, Institute of Genetic Medicine
• Genetica DNA Laboratories
• Genomics Core Laboratory (GCL), Augusta University
• Genomics Core, Sanford Burnham Preby Medical Discovery Institute
• GenoSeq, UCLA Genotyping and Sequencing Core
• German Cancer Research Center (DKFZ)
• German Collection of Microorganisms and Cell Cultures (DSMZ)
• GlaxoSmithKline (GSK)
• Global Biological Standards Institute (GBSI)
• Harrison Research Laboratories
• Hy Laboratories
• IDEXX BioResearch
• ILC Micro-Chem
• Illumina
• IndoBiotek Services
• Institute for Molecular Medicine Finland (FIMM)
• Institute of Health and Biomedical Innovation, Genomics Research Facility, Queensland University of Technology
• Integrated Systems Engineering
• Interdisciplinary Center for Biotechnology Research (ICBR), University of Florida
• International Cell Line Authentication Committee (ICLAC)
• Janssen Biotech
• KaryoLogic
• Laboratoire LCA
• LakePharma
• Laragen
• LGC Standards
• Li Ka Shing Faculty of Medicine, University of Hong Kong,
• Life Technologies
• Livogen pharmed
• Lonza
• MABION
• MaxCyte
• Merck
• Microbiology & Quality Associates
• Microsynth
• Ministry of Health, Labour and Welfare (MHRW)
• ModiQuest
• Molecular Biology Service Center, University of Colorado
• Molecular Cloning Laboratories (MCLAB)
• Molecular Cytogenetics Facility, MD Anderson Cancer Center, The University of Texas
• Molecular Diagnostic Services
• Monash Health Translation Precinct (MHTP) Medical Genomics Facility
• Moredun Scientific
• MTI-GlobalStem
• Multiplexion
• National Center for Biotechnology Information (NCBI)
• National Institute of Standards and Technology (NIST)
• National Institutes of Health (NIH)
• NorthGene
• Novartis
• Octapharma
• Oncotest
• Oxford Genetics
• Pharmaceutical and Food Safety Bureau (PFSB)
• Pharmaceuticals Medical Devices Agency (PMDA)
• ProBioGen
• Promega
• Protein Expression Laboratory, Frederick National Laboratory for Cancer Research
• Protein Sciences
• Protein Technologies
• Public Health England (PHE)
• QED Bioscience
• qGenomics
• R M Nardone Associates
• Research Technology Support Facility (RTSF) Genomics Core, Michigan State University
• Richter-Helm BioLogics
• RIKEN
• Rockland Immunochemicals
• Roswell Park Cancer Institute
• RUCDR Infinite Biologics
• Sanofi Pasteur
• SCIEX
• Sealy Center for Molecular Medicine, University of Texas Medical Branch
• Seqirus
• SGS
• Shannon McCormack Molecular Diagnostics Laboratory, Dana Farber Cancer Institute
• Shire
• Sigma-Aldrich
• Source BioScience
• Stem Cell and Transgenic Core Facility, College of Veterinary Medicine, Cornell University
• Stem Cell Core Facility, Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences
• Sumitomo Dainippon Pharma
• Texcell
• TFBS Bioscience
• The Centre for Applied Genomics (TCAG), Genetic Analysis Facility, The Hospital for Sick Children
• The Institute for Forensic Genetics (IFG)
• The University of Texas Southwestern Medical Center
• The Westmead Institute for Medical Research
• Thermo Fisher Scientific
• Tissue Culture Core facility, University of Texas Medical Branch (UTMB)
• Tissue Solutions
• Unit of High Technology (UAT), Vall d'Hebron Research Institute (VHIR)
• University of Arizona Genetics Core
• University of Leicester
• University of Sussex
• University of Vermont Cancer Center
• University of Washington
• USC Norris Comprehensive Cancer Center
• Valneva
• Vista Biologicals
• Vitrology
• Waisman Biomanufacturing
• Washington University Institute of Clinical and Translational Sciences (ICTS)
• Whittaker Corporation
• WiCell Research Institute
• WIL Research
• World Health Organization (WHO)
• WuXi AppTec
• WuXi Biologics

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