Accessibility Statement Skip Navigation
  • Resources
  • Blog
  • Journalists
  • +44 (0)20 7454 5110
  • Client Login
  • Send a Release
Return to PR Newswire homepage
  • News
  • Products
  • Contact
When typing in this field, a list of search results will appear and be automatically updated as you type.

Searching for your content...

No results found. Please change your search terms and try again.
  • News in Focus
      • Browse News Releases

      • All Public Company News
      • All Multimedia News
      • View All News Releases

      • Regulatory News

      • D/A/CH Regulatory News
      • UK Regulatory News
      • View All Regulatory News

  • Business & Money
      • Auto & Transportation

      • Aerospace & Defense
      • Air Freight
      • Airlines & Aviation
      • Automotive
      • Maritime & Shipbuilding
      • Railroads & Intermodal Transportation
      • Supply Chain/Logistics
      • Transportation, Trucking & Railroad
      • Travel
      • Trucking & Road Transportation
      • View All Auto & Transportation

      • Business Technology

      • Blockchain
      • Broadcast Tech
      • Computer & Electronics
      • Computer Hardware
      • Computer Software
      • Data Analytics
      • Electronic Commerce
      • Electronic Components
      • Electronic Design Automation
      • Financial Technology
      • High Tech Security
      • Internet Technology
      • Nanotechnology
      • Networks
      • Peripherals
      • Semiconductors
      • View All Business Technology

      • Entertain­ment & Media

      • Advertising
      • Art
      • Books
      • Entertainment
      • Film & Motion Picture
      • Magazines
      • Music
      • Publishing & Information Services
      • Radio & Podcast
      • Television
      • View All Entertain­ment & Media

      • Financial Services & Investing

      • Accounting News & Issues
      • Acquisitions, Mergers & Takeovers
      • Banking & Financial Services
      • Bankruptcy
      • Bond & Stock Ratings
      • Conference Call Announcements
      • Contracts
      • Cryptocurrency
      • Dividends
      • Earnings
      • Earnings Forecasts & Projections
      • Financing Agreements
      • Insurance
      • Investments Opinions
      • Joint Ventures
      • Mutual Funds
      • Private Placement
      • Real Estate
      • Restructuring & Recapitalisation
      • Sales Reports
      • Shareholder Activism
      • Shareholder Meetings
      • Stock Offering
      • Stock Split
      • Venture Capital
      • View All Financial Services & Investing

      • General Business

      • Awards
      • Commercial Real Estate
      • Corporate Expansion
      • Earnings
      • Environmental, Social and Governance (ESG)
      • Human Resource & Workforce Management
      • Licensing
      • New Products & Services
      • Obituaries
      • Outsourcing Businesses
      • Overseas Real Estate (non-US)
      • Personnel Announcements
      • Real Estate Transactions
      • Residential Real Estate
      • Small Business Services
      • Socially Responsible Investing
      • Surveys, Polls & Research
      • Trade Show News
      • View All General Business

  • Science & Tech
      • Consumer Technology

      • Artificial Intelligence
      • Blockchain
      • Cloud Computing/Internet of Things
      • Computer Electronics
      • Computer Hardware
      • Computer Software
      • Consumer Electronics
      • Cryptocurrency
      • Data Analytics
      • Electronic Commerce
      • Electronic Gaming
      • Financial Technology
      • Mobile Entertainment
      • Multimedia & Internet
      • Peripherals
      • Social Media
      • STEM (Science, Tech, Engineering, Math)
      • Supply Chain/Logistics
      • Wireless Communications
      • View All Consumer Technology

      • Energy & Natural Resources

      • Alternative Energies
      • Chemical
      • Electrical Utilities
      • Gas
      • General Manufacturing
      • Mining
      • Mining & Metals
      • Oil & Energy
      • Oil & Gas Discoveries
      • Utilities
      • Water Utilities
      • View All Energy & Natural Resources

      • Environ­ment

      • Conservation & Recycling
      • Environmental Issues
      • Environmental Policy
      • Environmental Products & Services
      • Green Technology
      • Natural Disasters
      • View All Environ­ment

      • Heavy Industry & Manufacturing

      • Aerospace & Defence
      • Agriculture
      • Chemical
      • Construction & Building
      • General Manufacturing
      • HVAC (Heating, Ventilation & Air-Conditioning)
      • Machinery
      • Machine Tools, Metalworking & Metallurgy
      • Mining
      • Mining & Metals
      • Paper, Forest Products & Containers
      • Precious Metals
      • Textiles
      • Tobacco
      • View All Heavy Industry & Manufacturing

      • Telecomm­unications

      • Carriers & Services
      • Mobile Entertainment
      • Networks
      • Peripherals
      • Telecommunications Equipment
      • Telecommunications Industry
      • VoIP (Voice over Internet Protocol)
      • Wireless Communications
      • View All Telecomm­unications

  • Lifestyle & Health
      • Consumer Products & Retail

      • Animals & Pets
      • Beers, Wines & Spirits
      • Beverages
      • Bridal Services
      • Cannabis
      • Cosmetics & Personal Care
      • Fashion
      • Food & Beverages
      • Furniture & Furnishings
      • Home Improvement
      • Household, Consumer & Cosmetics
      • Household Products
      • Jewellery
      • Non-Alcoholic Beverages
      • Office Products
      • Organic Food
      • Product Recalls
      • Restaurants
      • Retail
      • Supermarkets
      • Toys
      • View All Consumer Products & Retail

      • Entertain­ment & Media

      • Advertising
      • Art
      • Books
      • Entertainment
      • Film & Motion Picture
      • Magazines
      • Music
      • Publishing & Information Services
      • Radio & Podcast
      • Television
      • View All Entertain­ment & Media

      • Health

      • Biometrics
      • Biotechnology
      • Clinical Trials & Medical Discoveries
      • Dentistry
      • FDA Approval
      • Fitness/Wellness
      • Health Care & Hospitals
      • Health Insurance
      • Infection Control
      • International Medical Approval
      • Medical Equipment
      • Medical Pharmaceuticals
      • Mental Health
      • Pharmaceuticals
      • Supplementary Medicine
      • View All Health

      • Sports

      • General Sports
      • Outdoors, Camping & Hiking
      • Sporting Events
      • Sports Equipment & Accessories
      • View All Sports

      • Travel

      • Amusement Parks & Tourist Attractions
      • Gambling & Casinos
      • Hotels & Resorts
      • Leisure & Tourism
      • Outdoors, Camping & Hiking
      • Passenger Aviation
      • Travel Industry
      • View All Travel

  • Policy & Public Interest
      • Policy & Public Interest

      • Animal Welfare
      • Corporate Social Responsibility
      • Economic News, Trends & Analysis
      • Education
      • Environmental
      • European Government
      • Labour & Union
      • Natural Disasters
      • Not For Profit
      • Public Safety
      • View All Policy & Public Interest

  • People & Culture
      • People & Culture

      • Aboriginal, First Nations & Native American
      • African American
      • Asian American
      • Children
      • Diversity, Equity & Inclusion
      • Hispanic
      • Lesbian, Gay & Bisexual
      • Men's Interest
      • People with Disabilities
      • Religion
      • Senior Citizens
      • Veterans
      • Women
      • View All People & Culture

  • Overview
  • Distribution
  • Paid Placement
  • Multimedia
  • Disclosure Services
  • SocialBoost
  • Rooms
    • MediaRoom
    • ESG Rooms
  • AI Tools
  • General Enquiries
  • Media Enquiries
  • Partnerships
  • Hamburger menu
  • Cision PR Newswire UK provides press release distribution, targeting, monitoring, and marketing services
  • Send a Release
    • Phone

    • +44 (0)20 7454 5110 from 8 AM - 5:30 PM GMT

    • ALL CONTACT INFO
    • Contact Us

      +44 (0)20 7454 5110
      from 8 AM - 5:30 PM GMT

  • Client Login
  • Send a Release
  • Resources
  • Blog
  • Journalists
  • News in Focus
    • Browse News Releases
    • Regulatory News
  • Business & Money
    • Auto & Transportation
    • Business Technology
    • Entertain­ment & Media
    • Financial Services & Investing
    • General Business
  • Science & Tech
    • Consumer Technology
    • Energy & Natural Resources
    • Environ­ment
    • Heavy Industry & Manufacturing
    • Telecomm­unications
  • Lifestyle & Health
    • Consumer Products & Retail
    • Entertain­ment & Media
    • Health
    • Sports
    • Travel
  • Policy & Public Interest
    • Policy & Public Interest
  • People & Culture
    • People & Culture
  • Client Login
  • Send a Release
  • Resources
  • Blog
  • Journalists
  • Overview
  • Distribution
  • Paid Placement
  • Multimedia
  • Disclosure Services
  • Cision Communications Cloud®
  • AI Tools
  • Client Login
  • Send a Release
  • Resources
  • Blog
  • Journalists
  • General Enquiries
  • Media Enquiries
  • Partnerships
  • Client Login
  • Send a Release
  • Resources
  • Blog
  • Journalists

CAS Assigns the 100 Millionth CAS Registry Number® to a Substance Designed to Treat Acute Myeloid Leukemia


News provided by

Chemical Abstracts Service

29 Jun, 2015, 20:08 GMT

Share this article

Share toX

Share this article

Share toX

-- Assignment marks a double milestone for CAS REGISTRY(SM) which celebrates its 50th anniversary in 2015

COLUMBUS, Ohio, June 29, 2015 /PRNewswire/ -- Chemical Abstracts Service (CAS), the world's authority for chemical information, registered the 100 millionth chemical substance in the CAS REGISTRYSM, in the 50th anniversary year of the world's largest database of unique chemical substances.

Photo - http://photos.prnewswire.com/prnh/20150629/226685-INFO

Continue Reading
This image opens in the lightbox

With a steady increase in patenting activity around the globe, it is not surprising the 100 millionth small molecule registration comes from a patent.  In this case, the substance was reported in a World Intellectual Property Organization (WIPO) patent (WO 2015081280) from Coferon, Inc. (Coferon) in Stony Brook, NY.  The inventors claim the molecule, CAS RN 1786400-23-4, available in both SciFinder® and STN®, is a novel therapeutic designed to treat acute myeloid leukemia.

"Coferon is developing proprietary biorthogonal linkers for multiple therapeutic approaches," said Dr. Maneesh Pingle, vice president, operations & business development. "A particular focus is on novel silicon-based linkers such as in the recently registered molecule CAS RN 1786400-23-4. The CAS REGISTRY is an invaluable resource for scientists in academia and industry, and the research team at Coferon is delighted that the 100 millionth small molecule to be registered in the database was invented at Coferon."

From a humble beginning to a mainstay of chemical discovery
Started in 1965 as a project to uniquely identify and track chemical substance information, the CAS Registry system is the only complete and accurate source of unique identifiers, known as CAS Registry Numbers® for all organic and inorganic substances disclosed in scientific publications and other reputable sources.  Today, scientists, intellectual property professionals and compliance specialists around the world rely on CAS Registry Numbers to instantaneously identify and access the exact chemical needed for their research, safety and compliance needs.

The invention of CAS REGISTRY revolutionized the chemical information field and transformed research since the mid 60's, and CAS Registry Numbers are ubiquitous in mainstream society today.  Global regulatory organizations, including the United States Environmental Protection Agency and The ACT on the Registration and Evaluation of Chemicals regulatory body in Korea, require all new chemical substances manufactured or imported to be identified by a CAS Registry Number.  These are also used on Materials Safety Data Sheets (MSDS) around the world as a reliable resource for safe handling and transport of chemicals.  CAS Registry Numbers are found on consumer products we use, e.g., paint cans and shampoo labels, and are relied upon in numerous web information sources, including chemical suppliers sites, Wikipedia, PubChem, and ChemSpider, to provide the one unique key that can open the world of information about that substance.

The substantial growth in worldwide chemical discoveries over the past 10 years is reflected in CAS REGISTRY as shown in Figure 1.  A view of all substances added since 1965 shows the pace of research has significantly accelerated in the past ten years.  Of the 100 million substances in CAS REGISTRY, approximately 75 million were added over the past 10 years.  On average, CAS has registered 1 substance every 2.5 minutes over the past 50 years.

"During the past 50 years, CAS investments in technology facilitated our capacity to define and sustain industry-leading timeliness in delivering vital chemical information to researchers around the world," said Dr. Matthew J. Toussant, CAS senior vice president, product and content operations.  "In the early years of CAS REGISTRY, substance information was stored on index cards and later defined as a notation system using linear algebraic codes that could be stored on punch cards.  Now, of course, our fully electronic technologies and optimizations enable us to keep pace in analyzing these rapidly increasing chemical disclosures, as well as in delivering nearly instantaneous access of this information to researchers worldwide." 

With no signs that chemical innovation is slowing, the current pace of substances added to CAS REGISTRY over the next 50 years would suggest registration of more than 650 million new chemical substances.  If the past growth trajectory is any indication, that number may well be significantly higher.

What does the future hold for the pace of new scientific discoveries?  "Researchers around the globe are leading the way," said Toussant.

About CAS
Chemical Abstracts Service (CAS), a division of the American Chemical Society, is the world's authority for chemical information and related solutions. Dedicated to the ACS vision of improving people's lives through the transforming power of chemistry, the CAS team of highly trained scientists finds, collects and organizes all publicly disclosed substance information, creating the world's most valuable collection of content that is vital to innovation worldwide.  Scientific researchers and patent professionals around the world rely on a suite of research solutions from CAS that enable discovery and facilitate workflows.

Modal title

Contact PR Newswire

  • +44 (0)20 7454 5110
    from 8 AM - 5:30 PM GMT
  • General Enquiries
  • Media Enquiries
  • Partnerships

Products

  • Content Distribution
  • Multimedia Services
  • Disclosure Services
  • Cision Communications Cloud®

About

  • About PR Newswire
  • About Cision
  • Partnering Opportunities
  • Careers
  • APAC
  • APAC - Simplified Chinese
  • APAC - Traditional Chinese
  • Brazil
  • Canada
  • Czech
  • Denmark
  • Finland
  • France
  • Germany
  • India
  • Indonesia
  • Israel
  • Japan
  • Korea
  • Mexico
  • Middle East
  • Middle East - Arabic
  • Netherlands
  • Norway
  • Poland
  • Portugal
  • Russia
  • Slovakia
  • Spain
  • Sweden
  • United States
  • Vietnam

My Services

  • All News Releases
  • Customer Portal
  • Resources
  • Blog
  • Journalists
  • Data Privacy

Do not sell or share my personal information:

  • Submit via Privacy@cision.com 
  • Call Privacy toll-free: 877-297-8921

Contact PR Newswire

Products

About

My Services
  • All News Releases
  • Customer Portal
  • Resources
  • Blog
  • Journalists
+44 (0)20 7454 5110
from 8 AM - 5:30 PM GMT
  • Terms of Use
  • Privacy Policy
  • Information Security Policy
  • Site Map
  • RSS
  • Cookie Settings
Copyright © 2025 PR Newswire Europe Limited. All Rights Reserved. A Cision company.