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Buccal Drug Delivery Systems - 2015 Detailed Analysis On Technologies And Pipeline Development


News provided by

Research and Markets

12 Oct, 2015, 09:10 GMT

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DUBLIN, Oct. 6, 2015 /PRNewswire/ -- Research and Markets (http://www.researchandmarkets.com/research/6bn252/buccal_drug) has announced the addition of the "Buccal Drug Delivery Systems: Opportunities And Challenges In Buccal, Sublingual Films, Tablets & Sprays - Detailed Analysis On Technologies And Pipeline Development" report to their offering.

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Buccal drug delivery is a promising area for continued research with the aim of systemic delivery of orally inefficient drugs as well as a feasible and attractive alternative for non-invasive delivery of potent peptide and protein drug molecules. In 2014, sales of Suboxone sublingual film totalled approximately $1.3 billion in the U.S. while the total market grew to more than $1.7 billion, driven by a 11 percent increase in prescriptions. In 2014, Bunavail buccal film has received US approval which has similar bioavailability of suboxone with half of the dose of buprenorphine.

Other than drugs used for local actions (antifungal, antiviral), generally controlled substances like buprenorphine, naloxone and fentanyl are preferred to release the drug through buccal formulations. However, testosterone (striant) to treat low testosterone levels in men also approved through use of buccal system of delivery. In the US, drugs such as Isosorbide dinitarte, ergoloid delivered sublingually have been discontinued and nitroglycerin has been replaced with sublingual metered spray. Ergomar (ergotamine tartarate) marketed by Rosedale therapeutics is the only sublingual tablets available in the US market, priced $15 per pill. Subsys (fentanyl) developed by Insys therapeutics was the recent sublingual spray approved in the US for the treatment of breakthrough cancer pain.

Global pharma companies such as Biodelivery Sciences, Bioalliance pharma (Onexo), Meda pharma, Orexo, Generex, Teijin are actively involved in developing oral mucoadhesive buccal delivery systems while sublingual technology have been used by Teva, Sun pharma, Grunenthal, Neurax, Angelini, Sandoz, Ethypharm, Arrow generics, Purdue and Actavis pharma. Sublingual spray technology have been employed by the companies such as Insys therapeutics, Perrigo, Mist pharm, Regency, Novadel, Generex, GW Pharma and Pohl Boskamp in developing potential drugs for the patients.

Ease of administration and better compliance offered by delivering through buccal route offers advantages for patients and physicians over other Invasive route and oral ingestion will drive the market further in positive directions going forward. Novel buccal delivery such as soluble thin films, mucoadhesive films and rapidmist spray offers newer route of delivery for the generics that has lesser patients compliances.

This report will provide detailed analysis on buccal delivery systems in broader pharma market in finding companies and technologies and complexities involved in developing this unique high potential delivery system.

Key Topics Covered:

1. Introduction

2. Types of dosage forms

3. Transmucosal Delivery Systems: The Mouth

4. Potential Benefits of Buccal Films

5. Limitations and Challenges of Buccal delivery system

6. Buccal Films

7. Buccal Tablets

8. Sublingual films/Tablets

9. Other technologies used in buccal delivery systems

10. Oral Thin fast Dissolving Films (OTF) - Ideal Characteristics, Classification and Evaluation

Companies Covered

- Actavis

- Angelini

- Applied Pharma Research

- Ardana Biosciences

- Auxillium Pharma

- Barr

- Biodelivery Sciences

- Blue fish

- Cynapsus Pharma

- Ethypharm

- Galena

- Galenica

- Generex

- Grunenthal

- Indivior

- Insys

- Insys Therapeutics

- IntelGenx

- Intellidrug

- LTS Lohmann

- Meda Pharma

- Mist Pharma

- Mystic Pharma

- Neuraxpharm

- Novadel

- Novel Labs

- Nycomed

- Roxane

- Sandoz

- Sanofi

- Snoreeze

- Tapemark

- Tesa Labtec Pharma

- Teva

For more information visit http://www.researchandmarkets.com/research/6bn252/buccal_drug

Media Contact:

Laura Wood, +353-1-481-1716, press@researchandmarkets.net

Related Links

http://www.researchandmarkets.com

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