Alzheimer's Vaccine: AFFiRiS AG Announces Data on Lead Product AD02: Information on Efficacy

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ABA - Invest in Austria

11 Mar, 2011, 16:00 GMT

VIENNA, Austria, March 11, 2011 /PRNewswire/ -- Today, AFFiRiS AG presented the evaluation of secondary endpoints of a clinical phase I study of their Alzheimer's vaccine AD02. The programme has been successful in respect of stabilising the cognitive performance and body weight of subjects during the 18-month study period. In nine out of twelve subjects who had received the vaccine with adjuvants the cognitive capabilities were clearly better than would have been expected due to the disease's progress. In addition, Alzheimer's patients usually lose weight, since their sense of taste can be impaired or they forget to take in food. By contrast, a preservation of body weight was recorded in the vaccinated subjects.

In October 2008, AFFiRiS AG entered into a licensing and option agreement with GlaxoSmithKline Biologicals. The agreement has a potential total value of 430 million Euro of which 36 million has already been paid. "International corporations such as GlaxoSmithKline, Siemens, Boehringer Ingelheim or Merck have recognized Austria as a business location and are expanding their research capacities. Policy has created a suitable framework: a R&D quota of 2.76 percent of GDP in 2010 that should increase to 4 percent by 2020. This will also benefit the dynamic Austrian life sciences, which is currently making some of the most important deals of the European biotechnology industry with international institutional investors" comments Dr. René Siegl, Managing Director of the Austrian Business Location Agency ABA-Invest in Austria.

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