ALBANY, New York, April 17, 2018 /PRNewswire/ --

The TMR report has estimated that the global active pharmaceutical ingredients market will be worth US$219,601.9 by the end of 2023, mounting from its evaluated worth of US$151,591.7 as of 2017, showcasing a CAGR of 6.4% during the period of 2017 to 2023. The report has identified captive manufacturing a stronger segment than contract manufacturing in the API market, whereas synthetic chemical API are in greater demand than biological APIs. Additionally, branded prescription drugs are the leading drug type segment. The report has also gauged the potential of demand that can be expected during the aforementioned forecast period from the therapeutic areas of cardiovascular, NSAIDs, metabolic, neurological, oncology, musculoskeletal, and other usages as well as in the regions of North America, Asia Pacific, Europe, and the Rest of the World (RoW). Availability of technically efficient manpower and cost effectiveness is poised to turn India and thereby Asia Pacific a highly lucrative region in the near future.

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Prevalence of Chronic Diseases Driving Demand 

The healthcare industry has been on an upward curve in the past couple of decades as a result of economic growth of a number of developing countries and robust reimbursement mandates in developed nations. As a result, the pharmaceutical manufacturers are busier than ever, catering to expanding demand generated by the prevalence of chronic diseases. In addition to that, lifestyle inflicted diseases are on the rise too, apart from increasing percentage of geriatrics in the world's population. The analyst of the report also has highlighted the strengthening presence of Indian drug manufacturers in the API market. Indian API manufacturers have been investing to comply with the U.S. FDA regulations, and to win contracts from the U.S. based companies, and have been filing the drug master file (DMF) applications. All these factors are expected to reflect positively on the global active pharmaceutical ingredients market in the near future.

On the other hand, compliance with regulatory is the primary hurdle challenging the API market at every step of the way. The exporters of active pharmaceutical ingredients now have to abide by the good manufacturing practice (GMP) in the European region, while FDA is regulating quality assurance in the U.S. and other regions. According to the analyst, while these regulations are helping to improve and maintain quality of drugs, they are also restricting the API manufacturing market especially in developing economies from Asia-Pacific.

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A recent business and commerce study by Transparency Market Research (TMR) has detected that the value chain of the active pharmaceutical ingredient (API) market is supported by players who specialize in specific technologies, and as a result are maintaining an edge on the back of their expertise in production. Companies such as BASF, DuPont, Dow Chemicals, and Bayer are some of the leading chemical manufacturers. API manufacturing is gradually being concentrated in the Asia-Pacific countries, particularly India, with companies such as Sun Pharma, Teva, Takeda, Orchid Pharma, and Cipla being prominent players. Demand for specialized APIs for biological drugs is increasing gradually too, which makes for a segment that is dominated by players such as PolyPeptide Group, Bachem Group, Otsuka Chemicals, and Lonza.

Major challenge for specialized active pharmaceutical ingredient manufacturers is the optimization of economies of scale through application of sophisticated technologies and enter into long-term contracts with western drug manufacturers. Through time, API manufacturers have forward integrated to manufacture their own drugs in order to expand profit margins and better explore the pharmaceutical landscape.

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Key Takeaways: 

• The demand in the global active pharmaceutical ingredients market will propagate at a formidable CAGR of 6.8% during the forecast period of 2017 to 2023
• Competitive landscape is moderately consolidated to a handful of players as new entrants find it tough to overcome stringent regulations and quality checks in the API manufacturing, besides needing a substantial capital

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